This study evaluated the accuracy with which the dual-energy X-ray absorptiometer (Hologic QDR 4500A) measured fat-free mass (FFM), fat mass (FM), and hydration of FFM. In a study of 58 men and women (ages 70-79 yr), the QDR 4500A was found to provide a systematically higher estimate of FFM and lower estimate of FM than a four-component model of body composition. A correction factor from this s...

The aim of this study was to investigate the validity of the Tanita TBF 300A leg-to-leg bioimpedance analyzer for estimating fat-free mass (FFM) in Bangladeshi children aged 4-10 years and to develop novel prediction equations for use in this population, using deuterium dilution as the reference method. Two hundred Bangladeshi children were enrolled. The isotope dilution technique with deuteriu...

OBJECTIVE To compare whole-body fat mass and fat-free mass (FFM) in ambulatory patients with multiple sclerosis (MS) and control subjects without MS. DESIGN Nonrandomized controlled trial or cross-sectional study. SETTING An exercise physiology laboratory at a medical school. PARTICIPANTS Seventeen ambulatory patients with MS and 12 control subjects (all subjects were women). The median E...

Obesity and obesity-related diseases are among the most prominent health problems in Western countries. In the USA and Europe, more than 40% of the population is overweight [1]. Obesity is normally defined by the body mass index (BMI; kg/m2). BMI values between 18.5 and 24.9 kg/m2 are considered normal; individuals with BMI values from 25 to 29.9 kg/m2 are considered overweight, while those wit...

OBJECTIVE The aging-associated changes in body composition result in an increased cardiometabolic risk. A tremendous reduction of cardiovascular morbidity and mortality can be obtained by statin therapy. Statins are well tolerated, with myopathy as the most serious negative side effect. Some recently published studies indicate that the incidence of type 2 diabetes might be increased during inte...

OBJECTIVES To determine sex differences in the distribution of regional and total skeletal muscle (SM) using contiguous whole body magnetic resonance imaging (MRI) data, and to examine the relations between fat free mass (FFM) and total and regional SM masses. METHODS A total of 20 Japanese college students (10 women and 10 men) volunteered for the study. FFM was measured by two compartment d...

BACKGROUND Pre-natal and post-natal growth are associated with adult body composition, but the relative importance of growth in different periods of childhood is still unclear, particularly in stunted populations. METHODS We studied 358 women and 352 men measured as children in 1969-77 in four villages in Guatemala, and re-measured as adults in 2002-04 (mean age 32.7 years). We determined the...