Complex decision models in expert systems often depend upon a number of utilities and subjective probabilities for an individual. Although these values can be estimated for entire populations or demographic subgroups, a model should be customized to the individual's specific parameter values. This process can be onerous and inefficient for practical decisions. We propose an interactive approach...

Mathematically rigorous descriptions of key hypotheses and theories are becoming more common in neuroscience and are beginning to be applied to psychiatry. In this article two fictional characters, Dr. Strong and Mr. Micawber, debate the use of such computational models (CMs) in psychiatry. We present four fundamental challenges to the use of CMs in psychiatry: (a) the applicability of mathemat...