BACKGROUND Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder characterized by palmoplantar hyperkeratosis and early development of aggressive periodontitis. Although cathepsin C (CTSC) gene mutations have been established in about 70-80% of PLS patients, it is assumed that the patients may have dysfunctioning of immune defense mechanisms. OBJECTIVE To assess the associati...

The hotel industry before the COVID-19 pandemic experienced rapid development and growth. This study aims to analyze effect of teamwork training on employee performance at Lv8 Resort Hotel role as a mediator performance. research was conducted data collection using questionnaire. population is all employees who work Hotel. method determining sample saturated sampling. All collected SEM-PLS anal...

Penelitian ini bertujuan untuk mengetahui apakah lingkungan kerja berpengaruh dan keadilan organisasional terhadap kinerja pegawai, kepuasan kerja, pegawai pada, yang dimediasi oleh pada dinas perumahan kawasan permukiman Provinsi Maluku Utara. merupakan penelitian kuantitatif. Populasi dalam meliputi Dinas Perumahan Kawasan Permukiman Utara sebanyak 140 tetap maupun tidak tetap. Data analisis ...

This study aims to determine and analyze the effect of introverted extroverted personalities on student interest in entrepreneurship through motivation as a mediating variable. research method is quantitative. Respondents this were undergraduate students at Jambi University. The data analysis used Partial Least Square (PLS) using Smart PLS application. results showed that there was an influence...

When entering foreign markets, software firms need to make a fundamental choice on the distribution arrangements for software and related services. This choice may involve contracting with local partners or entering foreign markets through company-owned channels. This study focuses on analyzing such boundary choices of software product firms in international markets. Taking a knowledge-based pe...

In recent years, many firms have adopted outsourcing as a means to govern their information technology (IT) operations. While outsourcing is associated with several important benefits, it also entails risk. The main purpose of this study was to validate measures of the risk factors associated with outsourcing IT operations. Insights from transaction costs theory suggest that risk factors are in...

Lactoferrin (Lf) is a potential-targeting ligand for hepatocellular carcinoma (HCC) cells because of its specific binding with asialoglycoprotein receptor (ASGPR). In this present work, a doxorubicin (DOX)-loaded, Lf-modified, polyethylene glycol (PEG)ylated liposome (Lf-PLS) system was developed, and its targeting effect and antitumor efficacy to HCC was also explored. The DOX-loaded Lf-PLS sy...

Genomic selection involves computing a prediction equation from the estimated effects of a large number of DNA markers based on a limited number of genotyped animals with phenotypes. The number of observations is much smaller than the number of independent variables, and the challenge is to find methods that perform well in this context. Partial least squares regression (PLS) and sparse PLS wer...