Chemical analysis of an Australian marine sediment-derived Aspergillus sp. (CMB-M081F) yielded the new diketomorpholine (DKM) shornephine A (1) together with two known and one new diketopiperazine (DKP), 15b-β-hydroxy-5-N-acetyladreemin (2), 5-N-acetyladreemin (3), and 15b-β-methoxy-5-N-acetyladreemin (4), respectively. Structure elucidation of 1-4 was achieved by detailed spectroscopic analysi...

The total descendent potential of a simple singularity satisfies the Kac–Wakimoto principal hierarchy. Bakalov and Milanov showed recently that it is also a highest weight vector for the corresponding W -algebra. This was used by Liu, Yang and Zhang to prove its uniqueness. We construct this principal hierarchy of type D in a different way, viz. as a reduction of some DKP hierarchy. This gives ...

Thirty litres of fermentation broth was extracted from the newly isolated Streptomyces sp. strain TN17 and various separation and purification steps led to the isolation of three pure bioactive compounds (1-3). Compound 1: cyclo (L-Leu-L-Arg), a diketopiperazine 'DKP' derivative; 2: di-(2-ethylhexyl) phthalate, a phthalate derivative; and 3: cyclo 1-[2-(cyclopentanecarbonyl-3-phenyl-propionyl]-...

The present invention relates to produce multiple unit particle system (MUPS) of stabilized ramipril pellets, hydrochlorothiazide, diluents, superdisintegrants, and lubricants which produce better dissolution of the system for better bioavailability with improving stability and bioavailability of ramipril. More particularly, the present invention is directed for stabilized ramipril against deco...

The design, synthesis and conformational studies of a new b-hairpin mimic, 2, are described in this paper. The design towards hairpin 2 is based on the assembly of the bifunctional DKP-1 as a b-turn inducer, a peptidomimetic strand, namely 5-amino-2-methoxybenzhydrazide, to stabilize the formation of b-sheets, and finally a tetrapeptide sequence, GVVI, containing the hydrophobic residues Val, I...

The potential condition of fishery sector is indeed quite large in Central Bangka Regency. majority fishermen Regency still use traditional fishing gear and simple technology. number units used consists 370 lift net, 1,085 gillnets, 129 bubu, 60 sero, 125 rods 4 beach seines with a fleet 1,767 (DKP 2019). These types need to be assessed for performance selected superior as form optimizing find ...