Abstract Die automatisierte Glykan Assemblierung (AGA) auf festen Trägern ist heutzutage von unschätzbarem Wert, um die biologische Bedeutung komplexer Kohlenhydrate mit den anhaltenden Herausforderungen ihrer Synthese in Einklang zu bringen. Während AGA‐Plattformen Konstruktion vieler natürlicher Zucker verändert haben, steckt Validierung der wohldefinierter (positionsselektiv modifizierter) G...

A new series of polypeptide presynaptic antagonists (((w-agatoxins”) was purified from venom of the funnel web spider Agelenopsis aperta. Physiological data indicate that all of these peptides are antagonists of voltage-sensitive calcium channels. Although all three w-agatoxins (Aga) described here (w-Aga-IA, w-AgaIB, and w-Aga-IIA) block insect neuromuscular transmission presynaptically, bioch...

Androgenetic Alopecia (AGA) is the most common noncicatricial alopecia that leads to the progressive miniaturization of the hair follicle. Scalp terminal hairs are converted into vellus hairs, primarily due to two factors: genetic predisposition and hormonal stimulation. The incidence and prevalence of AGA increases with age. The onset of AGA is gradual, and when this pathology progresses, the ...

BACKGROUND Sera of patients with coeliac disease, containing IgA and IgG antigliadin antibodies (AGA) and various IgA autoantibodies, react with isolated enterocytes. AGA cross react with enterocyte antigens, one of which has been identified as calreticulin. AIMS To characterise the antigenic structures of gliadin, enterocytes, and calreticulin recognised by AGA from patients with active coel...

Altered levels of naturally occurring anti-glycan antibodies (AGA) circulating in human blood plasma are found in different pathologies including cancer. Here the levels of AGA directed against 22 negatively charged (sialylated and sulfated) glycans were assessed in high-grade serous ovarian cancer (HGSOC, n = 22) patients and benign controls (n = 31) using our previously developed suspension g...

OBJECTIVE Fetuses conceived by assisted reproductive technology (ART) and those that are small-for-gestational age (SGA) show cardiovascular remodeling in utero; however, these two conditions are often associated. We aimed to evaluate the differential effect of ART and SGA on fetal cardiac remodeling. METHODS This was a prospective cohort study of term singleton pregnancies seen at our depart...