Along with the changes of disease spectrum, medical models and health concept, people pay more and more attention to the diagnostic and therapeutic approaches of traditional Chinese medicine (TCM). With the effect assessment being changed from disease-based model to patient-based model, how to scientifically and objectively explain the validity of TCM has become the premise for further developm...

The theories of Traditional Chinese Medicine (TCM) originated from experiences doctors had with patients in ancient times. We ask the question whether aspects of TCM theories can be reconstructed through data analysis. To answer the question, we have developed a data analysis method called latent tree models and have used it to analyze several TCM data sets. This paper reports the results we ob...

OBJECTIVE The objective of this study was to assess the clinical effectiveness of Traditional Chinese Medicine (TCM) as an adjuvant therapy for recurrent respiratory papillomatosis. DESIGN The design of this study was a case series. LOCATION AND SUBJECTS: Fifty-one (51) patients with laryngeal papillomatosis who were treated at Keio University Hospital between May 1981 and April 2008 were inc...

Four human CD8+ T-cell subsets, naive (CCR7+CD45RA+), central memory (TCM, CCR7+CD45RA-), effector memory (TEM, CCR7-CD45RA-), and CD45RA+ effector memory cells (TEMRA, CCR7-CD45RA+) were compared for their capacity to proliferate and differentiate in response to antigen or homeostatic cytokines. Cytokine responsiveness and interleukin-15 receptor expression were low in naive T cells and progre...

Background. Achieving reproducibility in research design is challenging when patient cohorts under study are inconsistently defined. Traditional Chinese medicine (TCM) diagnosis is one example where inconsistency between practitioners has been found. We hypothesise that the use of a validated instrument may improve consistency. Biochemical biomarkers may also be used enhance reliability. Method...

Zheng is the basic theory and essence of traditional Chinese medicine (TCM) in diagnosing diseases. However, there are no biological evidences to support TCM Zheng differentiation. In this study we elucidated the biological alteration of cirrhosis with TCM "Liver-Kidney Yin Deficiency (YX)" or "Dampness-Heat Internal Smoldering (SR)" Zheng and the potential of urine metabonomics in TCM Zheng di...

Traditional Chinese medicine (TCM) has long been used for patients with psoriasis. This study aimed to investigate TCM usage in patients with psoriasis. We analyzed a cohort of one million individuals representing the 23 million enrollees randomly selected from the National Health Insurance Research Database in Taiwan. We identified 28,510 patients newly diagnosed with psoriasis between 2000 an...

The relationship between disease, syndrome and formula is thought to be one of the most significant problems in TCM clinical and basic practice presently. Generally speaking, syndrome is not only the core of TCM basic theory and syndrome differentiation, but also the bridge linking disease and formula, and the base of definite diagnosis and proper treatment [1]. However, it was pointed out rece...

Objective: This study aims to systematically review the efficacy of Traditional Chinese Medicine (TCM) for treatment of dry eye symptom (DES). Methods: PubMed, EMbase, MEDLINE, The Cochrane Library, VIP, CNKI, CBM and Wanfang databases were searched manually and automatically by computer. The published literatures about DES treated by TCM were collected. After selection, quality evaluation and ...

Traditional Chinese medicine (TCM; zhōng yī) syndrome groups are based on the symptoms of human diseases and guide the use of Chinese herbs. The aim of this study was to examine the effects of TCM syndrome groups on biochemical characteristics and quality of life (QOL) in women with metabolic syndrome (MS). Among the 1080 registered female patients screened at our outpatient clinic, a total of ...