We describe the isolation and genetic characterization of point mutations in gene delta, including a temperature-sensitive mutation (del(206)). Genetic methods enable the extraction of a delta mutation from the triple mutant (del,red,gam) and the construction of new genotypes, including del,red and del,gam double mutants. Tests of plating efficiency indicate gene delta is essential for normal p...

Tumor necrosis factor (TNF)-alpha has been identified as a major inducer of colony stimulating factor (CSF)-secretion by human vascular endothelial cells and fibroblasts. In the present study we assessed the capacity of TNFs to induce release of CSF-1 from highly purified peripheral blood monocyte preparations. Whereas monocytes do not accumulate CSF-1 messenger (m)RNA constitutively and conseq...

Virtual Sports Teacher is a Serious Ga me which is being developed by sports scientists, computer scientists an d media scientists, funded by the HM WK (hessian Ministry of science and art). The primary target group of the gam e are physical education teacher st udents. In the gam e they can practice the procedure of a typical sport lesson, learn how to tr eat pupils and arrange different sport...

Miscanthus is a leading perennial biomass crop that can produce high yields on marginal lands. Moisture content highly relevant quality trait with multiple impacts efficiencies of harvest, transport, and storage. The dynamics moisture during senescence overwinter ripening are determined by genotype × environment interactions. In this paper, unmanned aerial vehicle (UAV)-based remote sensing was...

Rhodococcus equi, a facultative intracellular bacterium, causes severe pneumonia in foals. Evidence suggests that most foals become infected very early in life, when they have immature or ineffective innate immune responses. This study evaluated the antimicrobial activity of gallium against R. equi, as a potential chemoprophylactic and therapeutic agent. Rhodococcus equi was grown in media with...

During the past few years, the generalized additive model (GAM) has become a standard tool for epidemiologic analysis exploring the effect of air pollution on population health. Recently, the use of the GAM has been extended from time-series data to spatial data. Still more recently, it has been suggested that the use of GAMs to analyze time-series data results in air pollution risk estimates b...

BACKGROUND Global acute malnutrition (GAM) is the sum of moderate acute malnutrition (MAM) and severe acute malnutrition (SAM). The use of different foods and protocols for MAM and SAM treatment can be cumbersome in emergency settings. OBJECTIVE Our objective was to determine the recovery and coverage rates for GAM of an integrated protocol with a single food product, ready-to-use therapeutic...

T hree years and a 12-place ju m p in the polls a p p a re n tly m ake a difference of $55 for Notre Dame students hoping to t r a v e l to th e NCAA h o c k e y regionals beginning tonight in Grand Rapids, Mich. S en io r Jo h n n y M cD erm ott has fond memories of traveling in 2004 to then-No. 13 Notre D am e’s only previous gam e in the NCAA hockey tournam ent. He got a bus trip, a box lunc...