In this paper, we propose an alternative covariance estimator to the robust covariance estimator of generalized estimating equations (GEE). Hypothesis tests using the robust covariance estimator can have inflated size when the number of independent clusters is small. Resampling methods, such as the jackknife and bootstrap, have been suggested for covariance estimation when the number of cluster...

BACKGROUND Analyses of multicenter studies often need to account for center clustering to ensure valid inference. For binary outcomes, it is particularly challenging to properly adjust for center when the number of centers or total sample size is small, or when there are few events per center. Our objective was to evaluate the performance of generalized estimating equation (GEE) log-binomial an...

AIMS To compare the results of a traditional approach using standard regression for the analysis of data from a prospective cohort study with the results of generalised estimating equations (GEE) analysis. METHODS The research was part of a three year prospective cohort study on work related risk factors for low back pain. The study population consisted of a cohort of 1192 workers with no low...

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We examine whether observable majoron emission in double beta decay can be compatible with the big-bang nucleosynthesis (NS) and the observed neutrino flux from SN1987A. It is found that the NS upper bound on He abundance implies that the majoron-neutrino Yukawa coupling constant g ≤ 9 × 10 and its maximal value is allowed only when the scalar quartic coupling constant λ is extremely small, λ ≤...

Data from ocean color (OC) remote sensing are considered a cost-effective tool for the study of biogeochemical processes globally. Satellite-derived chlorophyll, instance, is an essential climate variable since it helpful in detecting change impacts. Google Earth Engine (GEE) planetary scale data analysis. Along with OC data, such tools allow unprecedented spatial and temporal analysis water qu...