This study tests the hypothesis that the prevalence of severe clinical manifestations in Gaucher disease type 1 (GD1) patients at the time of treatment initiation has changed since alglucerase/imiglucerase enzyme replacement therapy (ERT) was approved in the United States (US) in 1991. US alglucerase/imiglucerase-treated GD1 patients from the International Collaborative Gaucher Group Gaucher Re...

BACKGROUND Enhanced recovery after surgery (ERAS) programs have been reported to be feasible and useful for maintaining physiological function and facilitating recovery after colorectal surgery. The feasibility of such programs in gastric surgery remains unclear. This study assessed whether an ERAS program is feasible in patients who undergo gastric surgery. METHODS The subjects were patients...

Presentation Preference: Oral or Poster Objectives: ERAS has prompted changes to practice across the surgical, anaesthetic and nursing professions that have minimised the surgical stress response and reduced length of hospital stay. The next goal for ERAS teams is to return patients to normal function as quickly as possible following discharge. Occupational therapists support patients to recove...

Within the large body of research in complex network analysis, an important topic is the temporal evolution of networks. Existing approaches aim at analyzing the evolution on the global and the local scale, extracting properties of either the entire network or local patterns. In this paper, we focus on detecting clusters of temporal snapshots of a network, to be interpreted as eras of evolution...

We extend the conceptual model developed by Amelinckx et al. (2008) by relating electronic reverse auction (ERA) project outcomes to ERA project satisfaction. We formulate hypotheses about the relationships among organizational and project antecedents, a set of financial, operational, and strategic ERA project outcomes, and ERA project satisfaction. We empirically test the extended model with a...

Public health policies continue to play important roles in national and international health reforms. However, the influence and legacies of the public health eras during which such policies are formulated remain largely underappreciated. The limited appreciation of this relationship may hinder consistent adoption of public health policies by nation-states, and encumber disinvestment from ineff...

REVIEW QUESTION/OBJECTIVE The objectives of this review are to identify the effectiveness of esophageal Doppler monitoring (EDM) for goal-directed fluid therapy on postoperative outcomes during abdominal surgery when an enhanced recovery after surgery (ERAS) program is implemented.The specific question of this review is: does the guidance of fluid management by EDM versus fluid management witho...

It is shown that the evolution of the density perturbations during certain eras of substantial entropy generation in the universe can be described in the scheme of the KPZ equation. Therefore, the influence on cosmological structure formation by stochastic forces arising from various dissipations can be studied through the universal characteristics of surface growth in d = 3 + 1 dimensions. We ...

To specify quality requirements for Web 2.0 applications we propose an integrated approach which considers features for contents, functionalities and services. In this work we discuss how to model internal quality, external quality and quality in use views taking into account not only the software characteristics – as those specified in the ISO 9126-1 quality modelsbut also the own features to ...

OBJECTIVE To examine implementing an enhanced recovery after surgery (ERAS) protocol for women undergoing major gynecologic surgery at an academic institution and compare surgical outcomes before and after implementation. METHODS Two ERAS protocols were developed: a full pathway using regional anesthesia for open procedures and a light pathway without regional anesthesia for vaginal and minim...