Although the epileptogenic properties of estrogens have been widely demonstrated in several models and species, the mechanism(s) by which estrogens can acutely change seizure parameters including after discharge and seizure duration remain remains to be determined. In the present study, we examined the role of NMDA (N-methyl-D-aspartate), non-NMDA and estrogenic receptors in estradiol benzoate ...

The impact of different school types on the progress made by their pupils is an important topic, with especial relevance to the ongoing debate about the value of the specialist schools programme (see Chitty, 2001; Croxford, 2001). With the advent of detailed and exhaustive national value-added datasets it would seem that it should be a plain and simple matter to tackle these questions using obj...

The problem addressed in this paper is the computation of elementary functions (exponential, logarithm, trigonometric functions, hyperbolic functions and their reciprocals) in fixed precision, typically the computer single or double precision.The method proposed here combines Shift-and-Add algorithms and classical methods for the numerical integration of ODEs: it consists in performing the Shif...

Modern computer architecture provides a special instruction|the fused multiply-add (FMA) instruction|to perform both a multiplication and an addition operation at the same time. In this paper newly developed radix-2, radix-3, and radix-5 FFT kernels that e ciently take advantage of this powerful instruction are presented. If a processor is provided with FMA instructions, the radix-2 FFT algorit...

The increasing gap between CPU and memory performance forces us to reevaluate design choices made in the past to optimize the CPU-memory interface. Ideally, all CPU operand traffic would remain on-chip. It is obviously not feasible to have the number of registers be on the order of main memory size and it is not clear that increasing L1 cache sizes has significant benefit.[10] Current instructi...