Hu, Ying-Li, Song Li, John Y.-J. Shyy, and Shu Chien. Sustained JNK activation induces endothelial apoptosis: studies with colchicine and shear stress. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H1593–H1599, 1999.—The disruption of microtubules by treating bovine aortic endothelial cells with 1027–1025 M colchicine caused apoptosis, as evidenced by DNA laddering and TdT-mediated dUTP nick e...

Tschakovsky, M. E., and R. L. Hughson. Ischemic muscle chemoreflex response elevates blood flow in nonischemic exercising human forearm muscle. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H635–H642, 1999.—We tested the hypothesis that forearm blood flow (FBF) might be reduced during forearm exercise when a vasoconstrictor response was evoked by calf exercise during calf ischemia (CE 1 I). In...

McGiff, John C., and John Quilley. 20-HETE and the kidney: resolution of old problems and new beginnings. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R607–R623, 1999.—The protean properties of 20-hydroxyeicosatetraenoic acid (HETE), vasoactivity, mitogenicity, and modulation of transport in key nephron segments, serve as the basis for the essential roles of 20-HETE in the re...

Conrad, Kirk P., Laurie J. Kerchner, and Monique D. Mosher. Plasma and 24-h NOx and cGMP during normal pregnancy and preeclampsia in women on a reduced NOx diet. Am. J. Physiol. 277 (Renal Physiol. 46): F48–F57, 1999.—We tested the hypothesis that nitric oxide (NO) biosynthesis increases during normal human pregnancy and decreases in preeclampsia. The major metabolites of NO, nitrate and nitrit...

Kohzuki, Hisaharu, Hiromi Misawa, Susumu Sakata, Yoshimi Ohga, Hiroyuki Suga, and Miyako Takaki. Energy expenditure by Ba21 contracture in rat ventricular slices derives from cross-bridge cycling. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H74–H79, 1999.—To clarify the energy-expenditure mechanism during Ba21 contracture of mechanically unloaded rat left ventricular (LV) slices, we measured...

Concannon, Patrick W., V. Daniel Castracane, Richard E. Rawson, and Bud C. Tennant. Circannual changes in free thyroxine, prolactin, testes, and relative food intake in woodchucks, Marmota monax. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1401–R1409, 1999.— Woodchucks (n 5 12–14/group) with circannual cycles entrained to northern versus southern hemisphere photoperiods wer...

Traynor, Timothy R.,Ann Smart, Josephine P. Briggs, and Jurgen Schnermann. Inhibition of macula densastimulated renin secretion by pharmacological blockade of cyclooxygenase-2. Am. J. Physiol. 277 (Renal Physiol. 46): F706–F710, 1999.—Previous results from our laboratory have shown that in the isolated perfused juxtaglomerular apparatus, nonselective inhibitors of cyclooxygenase (COX) activity ...