A quantitative structure-activity relationship (QSAR) modeling of the antimalarial activity of two diverse sets of compounds for each of two strains D6 and NF54 of Plasmodium falciparum is presented. The molecular structural features of compounds are presented by molecular descriptors (geometrical, topological, quantum mechanical, and electronic) calculated using the CODESSA PRO software. Satis...

By using O(7, 7) transformations, to deform D6–branes, we obtain half-supersymmetric bound state solutions of type IIA supergravity, containing D6, D4, D2, D0, F1-branes and waves. We lift the solutions to M-theory which gives half-supersymmetric M-theory bound states, e.g. KK6–M5–M5–M5–M2–M2–M2–MW. We also take near horizon limits for the type IIA solutions, which gives supergravity duals of 7...

We report the discovery of a new smectic-C{*} liquid-crystal phase with six-layer periodicity by resonant x-ray diffraction. Upon cooling, the new phase appears between the SmC{alpha}{*} phase having a helical structure and the SmC{d4}{*} phase with four-layer periodicity. This SmC{d6}{*} phase was identified in two mixtures which have an unusual reversed SmC{d4}{*}-SmC{*} phase sequence. The S...

We study type IIA orientifold compactifications with fluxes that give rise to perturbatively stable, non-supersymmetric AdS$_4$ vacua D6-brane gauge sectors. Non-perturbative instabilities can be mediated by D8-branes wrapped on the six internal dimensions $X_6$, if they reduce 4d membranes a charge $Q$ larger than its tension $T$. The mismatch $Q \neq T$ arises due i) curvature corrections and...

The NMR spectra of azo dyes, 5-arylazobarbituric (5a-g), 5-arylazo-1,3-dimethylbarbituric(6a-g) and 5-arylazothiobarbituric acids (7a-g) were studied in DMSO-d6 in differentconcentrations. An intramolecular hydrogen bond was observed and indicating that thehydrazone forms is mostly predominant. The peak of the hydrazone proton was severelybroadened and its chemical shift appeared at down field ...

This paper investigates the impact of bridge-pilling modifications on tidal flow at strait a human-altered mesotidal estuary (Cádiz Bay, Spain). The analysis was accomplished by combining (1) field data current velocities in cross-section close to pile recently built bridge, and (2) hydrodynamics results from calibrated tested DELFT3D numerical model study site. focused bridge piling effects in...