نتایج جستجو برای: فرایند تحلیل شبکهای anp

تعداد نتایج: 262643  

Journal: :Circulation 1991
G Takemura H Fujiwara M Mukoyama Y Saito K Nakao A Kawamura M Ishida M Kida T Uegaito M Tanaka

To investigate the ventricular expression of atrial natriuretic peptide (ANP) in human hypertrophic hearts, we conducted an immunohistochemical study of 130 endomyocardial biopsy specimens obtained from the right side of the ventricular septum (RVB), left ventricular free wall (LVB), or both from a total of 80 patients: 44 patients with hypertrophic cardiomyopathy (HCM), 14 with apical hypertro...

Journal: :Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 1997
L L Elias J Antunes-Rodrigues A C Moreira

The existence of a circadian rhythm of atrial natriuretic peptide (ANP) in humans is controversial. We studied the plasma ANP response to isotonic blood volume expansion in the morning and in the afternoon and its relationship with adrenocorticotropic hormone (ACTH)-cortisol diurnal variation in seven normal subjects. Basal plasma ANP level was similar in the morning (19.6 +/- 2.4 pg/ml) and in...

Journal: :Japanese heart journal 1992
G Seki K Suzuki T Nonaka K Nosaka S Taniguchi C Aizawa K Kurokawa

Acute and chronic experiments were performed in rats to examine whether atrial natriuretic peptide (ANP) has any beneficial effects on glycerol-induced acute renal failure (ARF). ANP infusion (Atriopeptin III, 1.0 microgram/kg+0.2 microgram/kg/min) improved the renal blood flow (RBF) and the glomerular filtration rate (GFR), and induced profound natriuresis in the early stage of ARF. By contras...

2011
Aniket Kumar Manoj G Tyagi

The atrial natriuretic peptide (ANP), a member of the natriuretic peptide family, is a cardiovascular hormone which possesses well defined natriuretic, diuretic and vasodilating properties. Most of the biological effects of ANP are mediated through its guanylyl cyclase coupled receptor. ANP and its receptors have been shown to be expressed and differentially regulated in the immune system, and ...

Journal: :Circulation 1993
T Tsutamoto T Kanamori N Morigami Y Sugimoto O Yamaoka M Kinoshita

BACKGROUND High levels of endogenous atrial natriuretic peptide (ANP) are thought to compensate the condition of patients with heart failure by reducing preload and afterload. However, recent reports have indicated that a high plasma ANP level is a prognostic predictor in patients with heart failure. Therefore, the role of endogenous ANP has not been clearly established in patients with heart f...

Journal: :Molecular vision 2005
Raquel Rollín Aránzazu Mediero Arturo Fernández-Cruz Raquel Fernández-Durango

PURPOSE Atrial natriuretic peptide (ANP) is a known vascular antipermeability and antiangiogenic factor, but its possible alteration during the early stages of diabetic retinopathy has not yet been explored. The present study sought to investigate the expression of ANP and its receptors using a model of streptozotocin (STZ) induced diabetes in the rat. METHODS Diabetes was induced in male Wis...

Journal: :Hypertension 2013
Valentina Cannone Brenda K Huntley Timothy M Olson Denise M Heublein Christopher G Scott Kent R Bailey Margaret M Redfield Richard J Rodeheffer John C Burnett

We analyzed the phenotype associated with the atrial natriuretic peptide (ANP) genetic variant rs5065 in a random community-based sample. We also assessed and compared the biological action of 2 concentrations (10(-10) mol/L, 10(-8) mol/L) of ANP and ANP-RR, the protein variant encoded by the minor allele of rs5065, on activation of the guanylyl cyclase (GC)-A and GC-B receptors, production of ...

2013
JIE WANG GANG WU BAOJIN MA JIANHUA WU DUAN CAI

The aim of the current study was to investigate the therapeutic effect of Tripterygium wilfordii Hook F multiglycosides (TWG) on gut barrier dysfunction in rats with acute necrotizing pancreatitis (ANP). ANP was induced in rats using 3.5% sodium taurocholate. The rats were divided into 3 groups: the sham operation (SO), ANP and ANP+TWG groups. Biochemical and pathological change of pancreatic t...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012
Hiroshi Kato Tomohiro Mizuno Masashi Mizuno Akiho Sawai Yasuhiro Suzuki Hiroshi Kinashi Fumiko Nagura Shoichi Maruyama Yukihiro Noda Kiyofumi Yamada Seiichi Matsuo Yasuhiko Ito

BACKGROUND Atrial natriuretic peptide (ANP) was recently reported to ameliorate fibrosis in the heart and experimental renal diseases and vascular thickening after balloon injury. Peritoneal fibrosis is an important complication of long-term peritoneal dialysis, and peritonitis is a factor in its onset. In the present study, we investigated the effects of ANP in a rat peritonitis-induced perito...

2005
Takayoshi Tsutamoto Naoki Morigami

Background. High levels of endogenous atrial natriuretic peptide (ANP) are thought to compensate the condition of patients with heart failure by reducing preload and afterload. However, recent reports have indicated that a high plasma ANP level is a prognostic predictor in patients with heart failure. Therefore, the role of endogenous ANP has not been clearly established in patients with heart ...

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