We utilized a recently developed long-term serum-free culture system for bovine parathyroid cells to detect antibodies in seven patients with autoimmune hypoparathyroidism (AHP). Antibodies were tested by indirect immunofluorescence methods and by cytotoxicity utilizing the chromium (51Cr) release technique. Seven AHP sera caused specific lysis [57 +/- 6% release of 51Cr vs. 5 +/- 1% for 56 con...

“The theory of decision analysis (DA) is designed to help the individual make a choice among a set of prespecified alternatives” (Keeney and Raiffa 1976, vii). Simply put, the basic DA problem is, How should a decision maker select from a given set of competing alternatives that are evaluated against conflicting objectives? Because operations research (OR) is the science of decision making, OR ...

A comparison of identified sympathetic neurons in the isolated intact superior cervical ganglion revealed that secretomotor, pilomotor, and vasoconstrictor cells differ in their action potential mechanisms and in their postsynaptic alpha(2)-adrenergic responses to 10 microM norepinephrine (NE). In normal saline, the half-width of the spike afterhyperpolarization (AHP) in secretomotor neurons (1...

In hippocampal neurons, the firing of a train of action potentials is terminated by generation of the slow afterhyperpolarization (AHP). Recordings from hippocampal slices have shown that the slow AHP likely results from the activation of small-conductance calcium-activated potassium (SK) channels by calcium (Ca(2+)) entry through L-type Ca(2+) channels. However, the relative localization of th...

The recent government tendering process being conducted in an electronic way is becoming an inevitable affair for numerous governmental agencies to further exploit the superiorities of conventional tendering. Thus, developing an effective web-based bid evaluation methodology so as to realize an efficient and effective government E-tendering (GeT) system is imperative. This paper firstly investi...

This study investigates the use of Analytic Hierarchy Process (AHP) in estimating the determinants of patients’ satisfaction towards service delivery in six public teaching hospitals located in southwest Nigeria. To do this, the study gathered data from primary sources under consideration. Following this, it adopted a cross-sectional survey research design adopted with the aid of an AHP based q...

Cluster I neurons of the suprachiasmatic nucleus (SCN), which are thought to be pacemakers supporting circadian activity, fire spontaneous action potentials that are followed by a monophasic afterhyperpolarization (AHP). Using a brain slice preparation, we have found that the AHP has a shorter duration in cells firing at higher frequency, consistent with circadian modulation of the AHP. The AHP...

The evaluation process of employee performance has been very vital and critical issue for companies that aim to reward employees for meeting their organizational goals and identify whether or not their objectives are met, and develop necessary action plans so that they can be achieved in near future. This selection process is so essential for companies due to the fact that wrong decisions may n...

In hippocampal and other cortical neurons, action potentials are followed by a slow afterhyperpolarization (sAHP) generated by the activation of small-conductance Ca(2+)-activated K(+) channels and controlling spike frequency adaptation. The corresponding current, the apamin-insensitive sI(AHP), is a well known target of modulation by different neurotransmitters, including acetylcholine (via M(...

OBJECTIVE New technologies have emerged in recent years for the disinfection of hospital rooms and equipment that may not be disinfected adequately using conventional methods. There are several hydrogen peroxide-based area decontamination technologies on the market, but no head-to-head studies have been performed. DESIGN We conducted a head-to-head in vitro comparison of a hydrogen peroxide v...