Phase-feeding (PF; Treatment 2) was tested relative to an NRC regimen (Treatment 1) to evaluate the impact of PF on broilers during the finisher period (42 to 63 d). Two modified PF treatments were also tested during this experiment: Treatment 3 involved lowering the amino acid requirements predicted with PF linear regression equations by 10% (PF10), Treatment 4 involved increasing the slope of...

In order to study the thermal stability of accelerated-curing PF resin, the curing behavior of fresh PF resin was investigated in the presence of single accelerator of methylolurea derivatives (MMU), magnesium hydrate (Mg(OH)2), 25% aqueous solution of sodium carbonate (Na2CO3), and propylene carbonate (PC). Also their optimum combination was added in fresh PF resin. The thermal stability of cu...

BACKGROUNDS/AIMS Few reports have validated the clinical postoperative pancreatic fistula (PF) after distal pancreatectomy. The study intended to validate the predictability for clinical PF of drain amylase and lipase and to find out more appropriate postoperative day (POD) for diagnostic criterion of PF. METHODS A total of 154 patients underwent distal pancreatectomy. We used the clinical da...

BACKGROUND As a serine/threonine protein kinase, p70S6K plays an important role in tumor cells. Evidence has revealed overexpression of p70S6K and phosphorylated p70S6K (p-p70S6K) in various tumor tissues, with these proteins identified as independent prognostic markers in non-small cell lung cancer (NSCLC). In this study, we explored the role of the p70S6K specific inhibitor PF-4708671 in NSCL...

Two trials were conducted to study the effect of multi-steps phase-feeding (PF) program on growth performance of broiler chickens from 1 to 24 and 1 to 39 d of age. The control group was the nutrient recommendation of Aviagen (2019) with a three-step PF program (1-10, 11-24 and 25-39 d of age). In the first trial, the control group was compared with an eight-step PF program (PF8), and in the se...

The platelet factor-4 variant, designated PF-4var/CXCL4L1, is a recently described natural non-allelic gene variant of the CXC chemokine platelet factor-4/CXCL4. PF-4var/CXCL4L1 was cloned, and the purified recombinant protein strongly inhibited angiogenesis. Recombinant PF-4var/CXCL4L1 was angiostatically more active (at nanomolar concentration) than PF-4/CXCL4 in various test systems, includi...

BACKGROUND Pancreatic fistula (PF) remains the most challenging complication after pancreaticoduodenectomy (PD). The purpose of this study was to identify the risk factors of PF and delineate its impact on patient outcomes. METHODS We retrospectively reviewed clinical data of 532 patients who underwent PD and divided them into PF group and no PF group. Risk factors and outcomes of PF followin...

We investigated the underlying mechanism for the potent proapoptotic effect of paeoniflorin (PF) on human glioma cells in vitro, focusing on signal transducer and activator of transcription 3 (STAT3) signaling. Significant time- and dose-dependent apoptosis and inhibition of proliferation were observed in PF-treated U87 and U251 glioma cells. Expression of STAT3, its active form phosphorylated ...

It is unclear whether any clinical and laboratory features are associated with pulmonary fibrosis (PF) in systemic sclerosis (SSc). We assessed these features using a database of 29 patients with SSc and anti-topoisomerase I antibodies and 68 patients with SSc and anticentromere antibody (ACA). Clinical features were not associated with the incidence of PF in patients with SSc and anti-topoisom...

Paeoniflorin (PF), a natural compound isolated from Paeoniae radix, has been shown to exert antitumor effects in various types of human cancers including glioma. However, the mechanism of action is not well understood. S-phase kinase-associated protein (Skp)2 functions as an oncogene in many cancers. In the present study, we investigated whether Skp2 mediates the anti-glioma activity of PF. We ...