Pulmonary fibrosis refers to a group of lung diseases characterized by inflammation, fibroblast proliferation, and excessive collagen deposition. Although the mechanisms underlying pulmonary fibrosis are poorly understood, current evidence suggests that epithelial injury contributes to the development of fibrosis. Regenerative medicine approaches using extracellular matrix (ECM) scaffolds have ...

OBJECTIVES To describe the diagnostic value of selective extended cervical mediastinoscopy (ECM) in combination with video-assisted mediastinoscopic lymphadenectomy (VAMLA) in mediastinal staging of potentially resectable left-sided lung carcinoma. METHODS Institutional report on 110 ECM procedures indicated for enlarged lymph nodes within the aorto-pulmonary (AP) zone on computed tomography....

• The ectomycorrhizal (ECM) symbiosis was historically considered restricted to the temperate zones, but recent studies have shown the importance of this symbiosis across the tropics. We examined ECM fungal diversity, host plant phylogeny and ECM host preferences in a rainforest dominated by the leguminous host plants Dicymbe corymbosa, Dicymbe altsonii and Aldina insignis. • Ectomycorrhizal fu...

Hydrogen sulfide (H2S) has anti‑inflammatory and neuroprotective properties, particularly during pathological processes. Experimental cerebral malaria (ECM), which is caused by vascular leakage into the brain, is characterized by inflammation, neurological deficits and cerebral hemorrhage. The present study investigated the correlation between ECM genesis and the levels of H2S. The results indi...

All available publications providing descriptions of ectomycorrhizas (ECM) were reviewed in order to build a database containing details on fungus forming the ECM, host tree, country where the material for description was collected, and habitat of the ECM. Other secondary data were also recorded. In all 1244 descriptions of ECM published since 1961 in 479 papers were reviewed. The number of dif...

Electrospinning In article 2202302 by Matt J. Kipper, Salman R. Khetani, and co-workers, novel methods are developed to electrospin decellularized porcine liver extracellular matrix (ECM) collagen I into nanofibers without needing synthetic polymer blends toward mimicking the complex composition topography of native ECM. Primary human hepatocytes display higher long-term functions on in monocul...

Extracellular matrix (ECM) proteins are secreted to the exterior of the cell, and function as mediators between resident cells and the external environment. These proteins not only support cellular structure but also participate in diverse processes, including growth, hormonal response, homeostasis, and disease progression. Despite their importance, current knowledge of the number and functions...

INTRODUCTION Decellularized extracellular matrix (ECM) has been shown to promote a regenerative response when administered at the site of a wound [1]. ECM is known to recruit perivascular stem cells, polarize macrophages in an anti-inflammatory manner, and increase collagen deposition at the site of implantation. However, little is known about the mechanisms or specific components of ECM that f...

Extracellular matrix (ECM) within the vascular network provides both a structural and regulatory role. The ECM is a dynamic composite of multiple proteins that form structures connecting cells within the network. Blood vessels are distended by blood pressure and, therefore, require ECM components with elasticity yet with enough tensile strength to resist rupture. The ECM is involved in conducti...

Cerebral malaria is the most severe complication of Plasmodium falciparum infection and accounts for a large number of malaria fatalities worldwide. Recent studies demonstrated that C5(-/-) mice are resistant to experimental cerebral malaria (ECM) and suggested that protection was due to loss of C5a-induced inflammation. Surprisingly, we observed that C5aR(-/-) mice were fully susceptible to di...