BACKGROUND Deceased-donor kidneys are exposed to ischemic events from donor instability during the process of donation after circulatory death (DCD). Clinicians may be reluctant to transplant DCD kidneys with prolonged cold ischemia time (CIT) for fear of an additional deleterious effect. METHODS We performed a retrospective cohort study examining US registry data between 1998 and 2013 of adu...

The biodegradation of iron-citrate complexes depends on the structure of the complex formed between the metal and citric acid. Ferric iron formed a bidentate complex with citric acid, [Fe(III) (OH)(2) cit] involving two carboxylic acid groups, and was degraded at the rate of 86 muM h. In contrast, ferrous iron formed a tridentate complex with citric acid, [Fe(II) cit], involving two carboxylic ...

BACKGROUND Diabetic heart disease is associated with tetrahydrobiopterin oxidation and high arginase activity, leading to endothelial nitric oxide synthase dysfunction. Sepiapterin (SEP) is a tetrahydrobiopterin precursor, and L-citrulline (L-Cit) is converted to endothelial nitric oxide synthase substrate, L-arginine. Whether SEP and L-Cit are effective at reducing diabetic heart disease is no...

Previously, we observed increased plasma arginine (ARG) concentrations after glutamine (GLN)-enriched diets, in combination with clinical benefits. GLN delivers nitrogen for ARG synthesis, and the present study was designed to quantify the interorgan relationship of exogenous L-GLN or GLN dipeptide, by enteral or parenteral route, contributing to intestinal citrulline (CIT) and renal de novo AR...

W artykule podjeto probe oszacowania efektu fiskalnego dzialan uszczelniaj?cych w zakresie podatku CIT, prowadzonych Polsce latach 2014–2018, tj. ich wplywu na rozmiar luki podatkowej i dochody podatkowe. tym celu zaproponowano ekonometryczn? metode kwantyfikacji zmian CIT oraz dekompozycji cze?c o charakterze cyklicznym strukturalnym. Otrzymane wyniki wskazuj?, ze skutek dzialania czynnikow st...

The Response Time Concealed Information Test (RT-CIT) can reveal that a person recognizes relevant item ( probe , e.g., murder weapon) among other irrelevant items controls ), based on slower responses to the compared controls. present paper assesses influence of test length (due practice, habituation, or fatigue) two key variables in RT-CIT: (a) probe-control differences and (b) classification...

We present Flexible Combinatorial Interaction Testing (F-CIT), which aims to improve the flexibility of combinatorial interaction testing (CIT) by eliminating necessity developing specialized constructors for CIT problems that cannot be efficiently and effectively addressed existing constructors. F-CIT expresses entities covered space valid test cases, from samples are drawn obtain full coverag...

Despite the P300-concealed information test's validity in detecting concealed memory when it is conducted immediately after the mock crime, whether the P300-CIT's detection efficiency is moderated by time delay remains unknown. Here, we conducted a mock crime study in which guilty participants were tested immediately after the mock crime or 1 month later. An innocent group was also tested. Assu...

Combinatorial Interaction Testing (CIT) approaches aim to reveal failures caused by the interactions of factors, such as input parameters and configuration options. Our ultimate goal in this line of research is to improve the practicality of CIT approaches. To this end, we have been working on developing what we call Unified Combinatorial Interaction Testing (U-CIT), which not only represents m...

A diet enriched with citrulline (CIT) reduces white adipose tissue (WAT) mass. We recently showed that CIT stimulated β-oxidation in rat WAT explants from young (2-4 months) but not old (25 months) rats. Here we show that both in old rats and high-fat-diet-fed young rats, uncoupling protein one (UCP1) mRNA and protein expressions were weaker than those in young control rats. Selectively in WAT ...