OBJECTIVES The aim of this study was to assess the role of serum markers of myocardial necrosis after cardiac surgery. BACKGROUND The role of serum troponin T (TnT) and creatine kinase-MB (CK-MB) for the risk stratification of patients after cardiac surgery remains undefined. METHODS Serum levels of TnT and CK-MB were measured from 224 patients every 8 h after cardiac surgery. The results o...

Methods After ethics’ committee approval and written informed consent all adult patients undergoing elective cardiac surgery between February and November 2014 were included. Exclusion criteria were urgent surgery, GFR < 60 ml/min/1.73m2), CK-MB > 4 Î1⁄4g/L and/or Hs-cTn > 14 ng/L at baseline. Hs-cTn and CK-MB were measured before induction of anaesthesia (baseline), upon arrival in the ICU and...

Using a highly sensitive monoclonal antibody kit for CKMB, significant release of small amounts of CK-MB isoenzyme after exercise stress test was detected 4 to 6 h after induction of ischemia. This occurred in ten out of 15 patients with ischemic heart disease (66 percent) and in only one of the 18 healthy subjects (5.6 percent) serving as a control group. In five patients with coronary artery ...

(i) A 66-year-old man; cause of death was a large myocarclial infarction, confirmed at autopsy. Total LDH = 19 x ULR (upper limit of the normal reference interval); LDH1 16%, LDH2 16%, LDH3 16%, LDH4 20%, LDH5 25%, LDH6 7%. Total CK = 16 x ULR; MM 70%, MB 21%, no BB. (ii) A 68-year-old woman, motor-vehicle accident, with ruptured thoracic aorta (grafted) and lacerated liver. No gross brain inju...

OBJECTIVES To determine the differences among the creatine kinase (CK) levels in the spermatozoa of subfertile men with mild, moderate, or severe oligospermia and to examine the differences in CK activity between infertile patients with various clinical diagnoses and a group of normal healthy donors (control). CK is a marker of sperm maturity that correlates with the sperm fertilizing capacity....

Background: Human embryonic stem cells (hESC), which are derived from the inner cell mass of the blastocysts, have been considered to be pluripotent cells. In this study we examine the differentiating potential of hESC into hepatocytes by characterization of the expression of endoderm and liver-specific genes. Methods: hESC were cultivated in suspension to form aggregates, the embryoid bodies. ...

AIM To assess the value of vimentin and cytokeratin (CK) intermediate filament proteins (IFPs) in distinguishing between nodular hyperplasia and carcinoma of the prostate and in predicting prognosis in prostatic cancer. METHODS Fifteen carcinomas and 49 cases of nodular hyperplasia were studied using frozen sections and monoclonal antibodies to CK and vimentin IFPs. RESULTS There was no sta...

Using a highly sensitive monoclonal antibody kit for CK-MB, significant release of small amounts of CK-MB isoenzyme after exercise stress test was detected 4 to 6 h after induction of ischemia. This occurred in ten out of 15 patients with ischemic heart disease (66 percent) and in only one of the 18 healthy subjects (5.6 percent) serving as a control group. In five patients with coronary artery...

The aim of the present study was to report the genetic and immunohistochemical profile of a rare case of lacrimal gland oncocytoma. A 20-year-old male underwent magnetic resonance imaging (MRI) due to viral encephalitis. Notably, the MRI revealed a multicystic tumor in the left lacrimal gland. A lateral orbitotomy was performed and the tumor was completely excised. Four months following surgery...