It is just 100 years since Marchand [1] identified choriocarcinoma as a tumour arising from placental villous trophoblast. Earlier description of similar tumours failed to identify their tissue of origin. Gestational Trophoblastic Disease (GTD) is the terminological umbrella now used to span the spectrum of cellular proliferations ranging from villous forms of hydatiform mole through invasive m...

Gestational trophoblastic disease (GTD) is a group of conditions that originate from the abnormal hyperproliferation of trophoblastic cells, which derive from the trophectoderm, the outer layer of the blastocyst that would normally develop into the placenta during pregnancy. GTDs encompass hydatidiform mole (HM) (complete and partial), invasive mole, gestational choriocarcinoma, placental-site ...

The World Health Organisation’s (WHO) classification of gestational trophoblastic disease includes complete, partial, invasive and metastatic hydatidiform mole, exaggerated placental site nodule or plaque and two malignant tumoursplacental site trophoblastic tumour and choriocarcinoma [1]. The incidence of gestational trophoblastic disease (GTD) in Sri Lanka according to a hospital based study ...

Transformations are a common technique used to linearize data so that simple linear regression can be applied. A common transformation used is the logarithmic transformation. This transforms data that follows an exponential pattern so that a straight line can be fit to it. In this study human chorionic gonadotropin (hCG) levels in women with gestational trophoblastic disease (GTD), which are kn...

We investigated the stability of certain erythrocytic enzymes as assayed qualitatively by fluorescence spot tests. Preservation of the activities of glucose6-phosphate dehydrogenase (GPD), pyruvate kinase (PK), triose phosphate isomerase (TPI), glutathione reductase (GTD), and NADH diaphorase (ND) in heparin, glucose-EDTA, or Alsever’s solution was studied at -20#{176}C and 30#{176}C. In Alseve...

Background: Gestational Trophoblastic Disease (GTD) is a heterogeneous group of diseases that includes partial and complete hydatidiform mole, invasive choriocarcinoma placental site trophoblastic tumour. The study aimed to determine the clinical presentation management options outcome GTD in patients admitted tertiary hospital Bangladesh.
 Materials methods: This prospective observational...

Abstract Objective To provide guidelines for surgery and reduce the incidence of fracture, this study analyzed relationship between femoral fracture related factors in direct anterior approach (DAA) total hip arthroplasty (THA) lateral decubitus position. Method A retrospective series 273 consecutive patients who underwent THA with DAA position was analyzed. Each performed by same surgeon a con...

Gestational trophoblastic disease is a spectrum of placental disorders ranging from benign molar pregnancies to the neoplastic conditions such as invasive mole and choriocarcinoma. These patients are identified early due to markedly elevated hCG levels and characteristic ultrasound findings. Uterine evacuation is the recommended treatment, while chemotherapy can be reserved for patients with re...