Here we show that blocking the adhesive function of alphavbeta3 integrin with soluble RGD ligands, such as osteopontin or cilengitide, promoted association of Rab-coupling protein (RCP) with alpha5beta1 integrin and drove RCP-dependent recycling of alpha5beta1 to the plasma membrane and its mobilization to dynamic ruffling protrusions at the cell front. These RCP-driven changes in alpha5beta1 t...

This paper proposes a real-time concurrency control protocol called Reduced Ceiling Protocol (RCP) for real-time database systems (RTDBS) consisting of hard and soft real-time transactions. The schedulability of hard real-time transactions can be improved by bounding the blocking time from soft real-time transactions. Different concurrency control strategies are proposed to resolve data conflic...

In this paper, we propose rapid control prototyping (RCP) for a robot soccer using the SIMTool that has been developed in Seoul National University, Korea for the control aided control system design (CACSD). The proposed RCP enables us to carry out the rapid design and the verification of controls for two-wheeled mobile robots (TWMRs), players in the robot soccer, without writing C codes direct...

The recumbent cycling position (RCP) has become increasingly popular in recent years as a mode of exercise and rehabilitation. However, subtle, but important, differences are expected to exist between the RCP and the standard, upright cycling position (SCP). The differences are due primarily to the altered orientation of the rider's lower extremities relative to gravity. In order to determine i...

The health burden from heatwaves is expected to increase with rising global mean temperatures and more extreme heat events over the coming decades. Health-related effects from extreme heat are more common in elderly populations. The population of Europe is rapidly aging, which will increase the health effects of future temperatures. In this study, we estimate the magnitude of adaptation needed ...

This study aimed to estimate genetic correlation between carcass grading and retail productivity traits and to estimate the correlated response on retail productivity traits through selection for carcass grading traits in order to assess the efficacy of indirect selection. Genetic parameters were estimated with the data from 4240 Hanwoo steers using mixed models, and phenotypes included carcass...

Many proteins are retrieved to the trans-Golgi Network (TGN) from the endosomal system through several retrograde transport pathways to maintain the composition and function of the TGN. However, the molecular mechanisms involved in these distinct retrograde pathways remain to be fully understood. Here we have used fluorescence and electron microscopy as well as various functional transport assa...

OBJECTIVE Pharmacological and lifestyle interventions are recommended for the reduction of stroke risk in people who have had a transient ischaemic attack (TIA). This study aimed to investigate the quality of secondary stroke prevention in primary care following diagnosis of TIA in a specialist clinic. METHODS Quality standards were identified from the Royal College of Physicians (RCP) nation...

Background. There is sparse literature examining the ICB phase of aerobic- and anaerobic-trained athletes. Measurements of ICB phase values of athletes can help to evaluate the sport’s physiological demands and understand the physiological adaptations in response to physical training. Objectives. The purpose of this study was to examine the relationship between the isocapnic buffering (IC...

Coat protein (CP) gene of sugarcane streak mosaic virus-AP isolate (SCSMV-AP) was expressed in E. coli and recombinant CP (SCSMV-AP rCP) was purified by linear sucrose density gradient centrifugation. Observation of purified SCSMV-AP rCP under electron microscope revealed the presence of potyvirus-like particles (PVLPs). The assembled particles were shown to encapsidate CP gene transcripts by s...