Faced with the shortcomings of conventional dialysis on a long-term basis, as illustrated by the dialysis-related pathology, a need for a new strategy exists to improve the overall quality of treatment in end-stage renal failure (ESRF) patients. On-line haemodiafiltration (HDF) seems to be the best therapeutic option to achieve this goal at the present time. By enhancing convective clearances t...

INTRODUCTION In cases of myeloma cast nephropathy in need of haemodialysis (HD), reduction of free light chains using HD with High-Cut-Off filters (HCO-HD), in combination with chemotherapy, may be associated with better renal recovery. The aim of the present study is to evaluate the effectiveness of haemodiafiltration (HDF) in reducing free light chain levels using a less expensive heat steril...

BACKGROUND Because hemodiafiltration (HDF) involves large amounts of ultra-filtration and substitution fluid infusion, its effects on serum electrolytes may be different from those of hemodialysis (HD). Serum sodium and blood pressures were compared between patients undergoing online HDF and high-flux HD (HFHD). METHODS Thirty-two of 101 patients on HFHD switched voluntarily to online HDF. Th...

Abstract Background Online hemodiafiltration (OL-HDF), whether in pre-dilution OL-HDF (pre-HDF) or post-dilution (post-HDF), is conducted to efficiently remove low molecular weight proteins from the blood of patients requiring dialysis. ? 2 -microglobulin (? -MG) and ? 1 (? are used as biomarkers evaluate removal efficiency OL-HDF. We aimed relationship between -MG reduction rates amount albumi...

BACKGROUND On-line haemodiafiltration (HDF) is a technique which combines diffusion with elevated convection and uses pyrogen-free dialysate as a replacement fluid. The purpose of this study was to evaluate the difference between conventional HDF (1-3 l/h) and on-line HDF (6-12 l/h). METHODS The study included 37 patients, 25 males and 12 females. The mean age was 56.5 +/- 13 years and durati...

HDF is a library and le format for storing and exchanging scientiic data. In the absence of a Java(TM) implementation of the HDF library, Java applications that need to directly access data in HDF les require a Java interface to the native code HDF library. This document describes the design of the Java interface for the HDF library and one prototype application, the Java HDF Viewer (JHV). Perf...

A significant and increasing number of chronic kidney disease (CKD) patients are treated with online hemodiafiltration (OL-HDF), even in the absence of more conclusive survival data. OL-HDF affords several clinical benefits including control of anemia of CKD, a common affliction in dialysis patients. In efforts to understand the underlying mechanisms that contribute to the purported benefits of...