BACKGROUND Primary biliary cirrhosis (PBC) is a chronic and progressive cholestasis liver disease. Bile salt export pump (BSEP) is the predominant bile salt efflux system of hepatocytes. BSEP gene has been attached great importance in the susceptibility of PBC and the response rate of ursodeoxycholic acid (UDCA) treatment of PBC patients. METHODS In this study, TaqMan assay was used to genoty...

Projection-based control (PBC) systems have significant engineering impact and receive considerable scientific attention. To properly describe closed-loop PBC systems, extensions of classical projected dynamical are needed, because partial projection operators irregular constraint sets (sectors) crucial in PBC. These two features obstruct the application existing results on existence completene...

background: in radiation therapy, the peripheral dose is important when anatomical structures with very low dose tolerances are involved. in this study, the two available calculation algorithms of the varian eclipse 8.6 treatment planning system(tps), the anisotropic analytic algorithm (aaa) and pencil-beam convolution (pbc) was used to compare measured and calculated peripheral dose distributi...

The aim of this study was to compare the effects of a single whole-body cryostimulation (WBC) and a partial-body cryostimulation (PBC) (i.e., not exposing the head to cold) on indices of parasympathetic activity and blood catecholamines. Two groups of 15 participants were assigned either to a 3-min WBC or PBC session, while 10 participants constituted a control group (CON) not receiving any cry...

AIM To investigate histological and immunohistochemical differences in hepatitis between autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) with AIH features. METHODS Liver needle biopsies of 41 PBC with AIH features and 43 AIH patients were examined. The activity of periportal and lobular inflammation was scored 0 (none or minimal activity) to 4 (severe), and the degree of hepati...

Between June 1989 and June 1992, 144 patients participated in sequential clinical trials using peripheral blood progenitor cells (PBC) as their sole source of hematopoietic rescue following high-dose chemotherapy. All patients had received prior extensive combination chemotherapy and had marrow defects that precluded autologous bone marrow transplantation (ABMT). PBC were collected according to...

This study aimed to test the diagnostic performance of a fully quantitative fibrosis assessment tool for liver fibrosis in patients with chronic hepatitis B (CHB), primary biliary cirrhosis (PBC) and non-alcoholic steatohepatitis (NASH). A total of 117 patients with liver fibrosis were included in this study, including 50 patients with CHB, 49 patients with PBC and 18 patients with NASH. All pa...

In this article we present an artifact due to the conventional use of periodic boundary condition (PBC) which produces misleading results on charge transport behavior at low field regime. When simulated using PBC, artifact produces a negative field dependence of mobility (NFDM) at low field regime even when the positional disorder is neglected. The artifact is due to the extra bias the carrier ...

Test system for Aero Hydraulic Pump (AHP) has many nonlinear characteristics. Take two control strategies, Neural Network Controller (NNC) and Passivity Based Controller (PBC), to control the speed of AHP for measuring its properties. The results gained from comparing and analyzing to these controllers show that under different outlet pressures of AHP PBC has good stability and robustness which...