The eyeball proptoses about 0.5 mM and increases in intraocular pressure (IOP) about 2 mmHg with voluntary widening of the lid fissure. The findings probably result from the retraction of the upper lid into the orbit, thus increasing the volume of orbit contents and forcing the eyeball forward. Decrease in IOP with repeated tonometry may result, in part, from decay of the increased pressure ind...

normal. (iv) Bulbar conjunctiva was quite normal. V the upper fornix a whitish swelling of the size of three-quarter of an inch by half an inch was Been, this swelling became much more marked on everting e upper lid when it was seen extending on the uine spect of the upper lid to about one-quarter of an in? Jove the lid margin and above the limbus. This veiling was cystic in feeling. (vi) Rest ...

Patients with Parkinson's disease (PD) receiving L-3,4-dihydroxyphenylalanine (L-DOPA, the gold-standard treatment for this disease) frequently develop abnormal involuntary movements, termed L-DOPA-induced dyskinesias (LID). Glutamate overactivity is well documented in PD and LID. An approach to manage LID is to add to L-DOPA specific agents to reduce dyskinesias such as metabotropic glutamate ...

ion of Models of Stress Corrosion Cracking of Drip Shield and Waste Package Outer Barrier and Hydrogen Induced Corrosion of Drip Shield TABLE OF CONTENTS Page 1. PU R P O SE ............................................................................................................................... 8 2. QUALITY ASSURANCE .............................................. 8 3. COMPUTER SOFTWARE AN...

Although levodopa therapy remains the most effective symptomatic treatment for PD, its usefulness may be limited by these motor complications, which result in deterioration in quality of life. Levodopa-induced dyskinesia (LID) is characterized by a variety of hyperkinetic movements. Although chorea and dystonia are the most common manifestations of LID, stereotypies, tics, myoclonus, or ballism...

Sixty-one lid-loading procedure, performed by the author, were evaluated prospectively. Simple, gold weight implantation, combined with lower lid retractor recession, placement of fascia lata, and lateral tarsal strip tightening is effective for promoting voluntary closure and correction of lower lid paralytic ectropion. Placement of a heavier gold weight, in combination with mullerectomy, is a...

Rhythmic movements of the upper eyelids are infrequent manifestations of brain-stem disease. Gowers (1879) noted the close coordination between movements of the upper lids and eyeballs in vertical nystagmus. He attributed this coordinated movement to the natural synkinesis of the levator palpebrae superioris and superior rectus muscles; this clinical observation was later verified electrophysio...

We studied the relation between prostaglandin analogue use and ocular adnexal features. We used a prospective, cross-sectional study involving 157 current, 15 past, and 171 never users of prostaglandin analogues. Patients 50 years of age or older and without conditions affecting ocular adnexal anatomy underwent glaucoma medication use history, external digital photography and systematic externa...

To explore the limitations of the liver-specific IGF-I gene-deficient (LID) model and to further evaluate the role of endocrine IGF-I in early postnatal life and old age, we have studied these mice during the prepubertal period (from birth to 3 wk of age) and when they are 2 yr old. During the first 2 wk of life, IGF-I gene deficiency and the resulting reduction in serum IGF-I levels in LID mic...