Do transgenic crops cause agrobiodiversity erosion? We hypothesize that they increase productivity and reduce production risk and may therefore reduce farmer demand for onfarm varietal diversity, especially when only a few transgenic varieties are available. We also hypothesize that varietal diversity can be preserved when more transgenic varieties are supplied. These hypotheses are tested and ...

The tum gene of coliphage 186, encoded on a LexA controlled operon, is essential for UV induction of a 186 prophage. Primer extension analysis is used to confirm that Tum is the sole phage function required for prophage induction and that it acts against the maintenance repressor, CI, to relieve repression of the lytic promoters, pR and pB, and thereby bring about lytic development. In vitro ex...

Hypertrophy and inflammation of the synovium with various underlying pathologies - such as rheumatoid arthritis, osteoarthritis, haemophilia and spondyloarthropathy - can be treated successfully by radiosynoviorthesis (RSO). For medium-sized joints (shoulder, elbow, wrist, hip and ankle), the radionuclide of choice is rhenium-186. We review the evidence for the efficacy of this local, relativel...

We present a deep Giant Metrewave Radio Telescope (GMRT) search for HI 21 cm emission from three dwarf galaxies, viz. POX 186, SC 24 and KKR 25. Based, in part, on previous single dish HI observations, these galaxies have been classified as a BCD, a dwarf irregular and a transition galaxy respectively. However, in conflict with previous single dish detections, we do not detect HI in SC 24 or KK...

Samenvatting 185 Abstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 Samenvatting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186

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MicroRNAs can function as key tumor suppressors or oncogenes and act as biomarkers for cancer diagnosis or prognosis. Although high-throughput assays have revealed many miRNA biomarkers for pancreatic ductal adenocarcinoma (PDAC), only a few have been validated in independent populations or investigated for functional significance in PDAC pathogenesis. In this study, we correlated the expressio...