UNLABELLED A number of men receiving prolonged suppressive highly active antiretroviral therapy (HAART) still shed human immunodeficiency virus (HIV) in semen. To investigate whether this seminal shedding may be due to poor drug penetration and/or viral production by long-lived cells within male genital tissues, we analyzed semen and reproductive tissues from macaques chronically infected with ...

HIV-positive people who use drugs (PWUDs) are particularly vulnerable for suboptimal access to highly active antiretroviral therapy (HAART). We conducted a systematic review to identify factors associated with suboptimal HAART access among this population. Studies evaluating HAART access among active PWUDs as a primary outcome, presenting multivariate analysis and conducted after January 1997 w...

OBJECTIVE To assess hematologic and hepatic toxicities associated with in utero and breastfeeding exposure to maternal highly active antiretroviral therapy (HAART) among infants in Botswana. DESIGN A nested cohort study within a randomized clinical trial (the Mashi Study). Laboratory toxicities among infants born to women who initiated HAART before delivery were compared with toxicities among...

Purpose: To assess the long-term effect of highly active antiretroviral therapy (HAART) on biochemical parameters of HIV-infected patients in University of Benin Teaching Hospital (UBTH), Benin City, Nigeria. Methods: HIV/AIDS patients on HAART for 2 8 years (297), those who were not on HAART (112, positive control), and healthy subjects (103, negative control) were recruited in the Infectious ...

BACKGROUND Adherence to highly active antiretroviral therapy (HAART) has been proven to be the only effective treatment for HIV/AIDS worldwide. Good adherence to HAART might require good family support. OBJECTIVE To determine the family dynamics and social support of people living with HIV/AIDS (PLWHA) and its roles on HAART adherence at an ARV treatment clinic in Osogbo, Nigeria. METHOD De...

BACKGROUND The introduction of highly active antiretroviral therapy (HAART) led to a decreased incidence of the most severe opportunistic infections (OIs) in HIV-infected patients. In Poland, HAART became widely used in 1998. MATERIALS AND METHODS This study was based on data from medical records data collected in the years 2000-2002 from medical centers for HIV-infected patients in Poland. T...

OBJECTIVE To assess whether complementary and alternative medicine (CAM) use is associated with the timing of highly active antiretroviral therapy (HAART) initiation among human immunodeficiency virus (HIV)-infected participants of the Women's Interagency HIV Study. STUDY METHODS Prospective cohort study between January 1996 and March 2002. Differences in the cumulative incidence of HAART ini...

BACKGROUND The impact of highly active antiretroviral therapy (HAART) on health-related quality of life (QOL) of HIV-1 infected individuals in large prospective cohorts has not been well studied. OBJECTIVE To assess the effect of HAART on QOL by comparing HIV-infected women using HAART with HIV-infected women remaining HAART naïve in the Women's Interagency HIV Study (WIHS), a multicenter pro...

UNLABELLED BACKGROUND Data on lipid profile abnormalities among patients receiving highly active antiretroviral treatment in Ethiopia are very limited. The aim of this study was to determine the prevalence of dyslipidemia and characteristics of lipid profiles among patients living with human immunodeficiency virus (HIV) using first-line highly active antiretroviral therapy (HAART) in Souther...

Objective: To ascertain the prevalence of cervical dysplasia and the relationship between the degree of cervical dysplasia and HAART in HIVpositive women. Method: This was a cross-sectional study involving 250 HIV positive women on HAART attending the HIV clinic of the University of Port Harcourt Teaching Hospital (UPTH). Cervical smears were collected from participants, examined and reported u...