Background Over-the-counter (OTC) medicines are available without prescription, allowing convenience and facilitating self-care. As more OTC drugs become available, concerns regarding misuse have increased. This study explored pharmacists’ perceptions about OTC drugs misuse, products involved and measures taken to address misuse. Methods This was a cross-sectional postal survey. A questionnaire...

Use of antibiotic-contaminated manure in crop production poses a severe threat to soil and plant health. However, few studies have studied the mechanism by which plant development is affected by antibiotics. Here, we used microscopy, flow cytometry, gene expression analysis and fluorescent dyes to study the effects of oxytetracycline (OTC), a widely used antibiotic in agriculture, on root meris...

Antibiotics are considered an important primary therapy for bacterial diseases in aquaculture. This study evaluated the influence of oral administration oxytetracycline (OTC) on feed intake, growth, mortality, residue accumulation and clearance, histopathological changes vital organs six groups Nile tilapia Oreochromis niloticus when fed at 0–10 times therapeutic dose (1×: 80 mg/kg biomass/day)...

The availability of over-the-counter (OTC) proton pump inhibitors (PPIs) for the short-term (2 weeks) management of frequent heartburn (≥2 days/week) has increased markedly, yet evidence-based recommendations have not been developed. A panel of nine international experts in gastroesophageal reflux disease developed consensus statements regarding the risks and benefits of OTC PPIs using a modifi...

BACKGROUND Medication complexity is a large determinant of adherence. Few studies have explored the relationship between cognitive impairment and medication complexity. OBJECTIVE To evaluate whether cognitive impairment is associated with medication complexity for prescription and over-the-counter (OTC) medications. METHODS In this cross-sectional analysis, we studied the association betwee...

Tetracyclines (TCs) are broad-spectrum antibiotics that are used widely in veterinary medicine. The present study was carried out to trace the residues of oxytetracycline (OTC) and tetracycline (TC) in pasteurized milk that is marketed in Tehran with the use of a High Performance Liquid Chromatography (HPLC). Ninety milk samples were collected during five sequential days from the products of si...

BACKGROUND Self-medication and acquisition of over-the-counter (OTC) medications are emerging community health issues. Besides being a cheap alternative for treating common illnesses, the behavior entails serious ramifications, such as medication wastage, increasing pathogen resistance, and adverse drug reactions. The present study was conducted to explore the extent of OTC medications in house...

Over-the-counter (OTC) medications are a fast developing branch of the pharmaceutical industry, in both Poland and rest of the world. The aim of the work was to evaluate the factors that influence the purchase and use of OTC medications in prevention and treatment of upper respiratory tract infections. The analysis involved 450 randomly chosen subjects, aged 19-80. The study was performed using...

Ornithine transcarbamylase (OTC) deficiency is well known for its diagnosis in the neonatal period. Presentation often occurs after protein feeding and manifests as poor oral intake, vomiting, lethargy progressing to seizure, respiratory difficulty, and eventually coma. Presentation at adulthood is rare (and likely underdiagnosed); however, OTC deficiency can be life-threatening and requires pr...

The current method for staging in gastric cancer is not sufficient as even after a complete primary tumor resection, patients with node-negative gastric cancer suffer from disease recurrence. In this study, the relation between disease recurrence and the presence of occult tumor cells (OTC) in lymph nodes from gastric cancer patients was evaluated. In a case-control design, lymph nodes from 40 ...