Phosphocreatine (PCr) is an endogenous compound containing high-energy phosphate bonds. It has been confirmed that PCr is effective in preventing and treating cardiac and renal ischemia-reperfusion injury. In this study, rat cerebral ischemia-reperfusion injury models were constructed. Apoptotic cells in the cortex region were measured by TUNEL method. Malondialdehyde (MDA) content was detected...

The aim of this work was to analyze the cell proliferation and apoptosis indexes on the 18 and 21 days of pregnancy of diabetic rats and to correlate with maternal glycemia and perinatal outcomes. Placentas from 20 Wistar rats were collected and divided into four experimental groups: control and diabetic of 18 and 21 days of pregnancy. The cell proliferation was analyzed using the PCNA expressi...

Purpose: The aim of the study explores probable toxic effects vancomycin on kidney and analysis protective melatonin.
 Materials Methods: In this study, rats were randomly divided into 4 groups: control group; melatonin (10 mg/kg/day) vancomycin-treated (200 mg/kg) + group. Rats in treatment group given two doses a day with an interval seven consecutive days once daily for days. experiment...

در پژوهش حاضر، پس از مطالعه مبانی نظری کارت امتیازی متوازن و بررسی راه‌حل‌های ارائه‌شده برای بهبود کاربرد آن توسعه نقشه استراتژی اهداف استراتژیک که روشن‌کننده مسیر حرکت سازمان رشد دستیابی به سازمانی است، مدلی پیشنهاد می­شود تا با نگاهی نو کاربردی، روابط تعیین اولویت‌بندی شوند. این پژوهش، نقاط قوت ضعف فرصت‌ها تهدیدهای اولویت‌دار به‌عنوان معیارهای ارزیابی نظر گرفته‌ شده است؛ سپس استفاده تکنیک تاپ...

اخیراً داده‌ها در سازمان‌ها به دارایی ارزشمندی تبدیل شده‌اند و حاکمیت داده یکی از اولویت‌های شده است. بررسی مطالعات پیشین نشان می‌دهد که سنجش استقرار به‌صورت کیفی انجام می‌شود نمی‌توانند بر اساس این نوع برنامه‌ای را برای بهبود وضعیت خود تعیین کنند. هدف پژوهش، ارائه روشی کمّی سطح یک سازمان متعاقباً برنامه‌ریزی موجود با توجه ماهیت عوامل تأثیرگذار میزان مفاهیم فازی مدل‌سازی تحلیل استفاده است؛ همچنین ...

Mesangial cell (MC) injury is a characteristic feature in the early phase of Thy.1 nephritis. The present study investigates the contribution of complement to MC apoptosis in this experimental model of kidney disease in rats. Thy.1 nephritis was induced by injection of mouse anti-Thy.1 monoclonal antibody (ER4G). To assess the contribution of the terminal sequence of complement on apoptosis, th...

BACKGROUND Osteonecrosis of the femoral head is classified into idiopathic and secondary forms. A number of etiological factors in the development of osteonecrosis have been suggested but the biological mechanisms are still unclear. Recently, some reports suggested that the apoptosis is closely related to osteonecrosis of the femoral head. Therefore, this study examined the expression of apopto...

Background—The terminal transferase uridyl nick end labelling (TUNEL) assay allows the easy demonstration of cell death as a result of apoptosis. However, when this assay is applied to liver tissue, the number of TUNEL positive cells is dependent on the time of incubation with proteinase K. Aim—To test whether false positive results are the result of the release of endogenous endonucleases by p...