UNLABELLED A simplified technique using (123)I-N-isopropyl-p-iodoamphetamine ((123)I-IMP) autoradiography (ARG) with SPECT has been proposed recently for quantifying regional cerebral blood flow (rCBF). To validate the accuracy of (123)I-IMP-ARG for quantifying regional cerebrovascular reactivity (rCVR) to acetazolamide, we compared rCVR determined using (123)I-IMP-ARG with that determined usin...

The effect of nitric oxide synthase (NOS) inhibition and endothelin-A (ETA)-receptor blockade on neural sympathetic control of vascular tone in the gastrocnemius muscle was examined in anesthetized dogs under conditions of constant flow. Muscle perfusion pressure (MPP) was measured before and after NOS inhibition (Nomega-nitro-L-arginine methyl ester; L-NAME) and ETA-receptor blockade [cyclo-(D...

“Over the Internet, no one knows you're a dog,” goes the joke. Yet, in most systems, a password submitted over the Internet gives one the same access rights as one typed at the physical console. We promote an alternate approach to authentication, in which a system fuses observations about a user into a probability (an authentication confidence) that the user is who they claim to be. Relevant ob...

International flows of high-skilled talent from developing countries to high-income OECD countries have grown in recent decades. Between 1970 and 1997, the number of foreign-born individuals in science and engineering occupations in the United States increased at three times the rate as that of natives, going from 7.6 percent in 1970 to 15 percent in 1997 (D’Costa, 2008). More recent data from ...

predicate P whenever it is possible, instead of using a catalog of theta-roles, which are difficult to justify. The use of abduction operations is limited hereto predicates already present in the core event structure. In other words, predicatesfrom the OS introduced by the core event are tried first. In this case, the OS [:at(z,y), at(z, y)] encodes the change of location that i...

In the title compound, C(12)H(15)NO(3), all C, N and O atoms lie in a mirror plane. An intramolecular C-H⋯O hydrogen bond is present.

In the crystal of the title compound, C(6)H(7)N(2)O(+)·C(2)HF(2)O(2) (-), the cation adopts a catemeric N-H⋯O hydrogen-bonded chain motif involving the carboxamide group, with two further N-H⋯O hydrogen bonds connecting the cations to adjacent difluoro-acetate anions via the carboxamide and pyridinium N atoms. The carboxamide group of the nicotinamidium ion is twisted by 32.3 (6)° from the pyri...

Objectives. Studies comparing outcome of single-(99m)Tc-methoxyisobutylisonitrile ((99m)Tc-sestamibi) and dual-tracer (99m)Tc-sestamibi scintigraphy in combination with (123)I before primary surgery of primary hyperparathyroidism (PHPT) are scarce. Methods. We compared (99m)Tc-sestamibi/(123)I and (99m)Tc-sestamibi in a single-centre retrospective series of 269 PHPT patients. The results were r...

The total cellular content of the fluorescent mitochondrialspecific dye rhodamine 123 (Rh-123) was quantified by butanol extraction as a function of time of exposure and dose for a variety of cell lines. These results were compared with observa tions made by fluorescence microscopy on dye localization and mitochondrial morphology. There appeared to be two categories of cell types based on Rh-12...