記憶はまず海馬で形成された後，脳の他領域に移行する．この時シナプス長期増強現象（LTP）が起こると考えられるが，いつどこで起こるかは明らかではない．そこで光にてLTPを解除する手法を確立し，海馬では学習時にだけではなく，同日の睡眠中にも起こること，大脳皮質では次の日の睡眠中にLTPが起こることを示した．

Acute intrahippocampal infusion of brain-derived neurotrophic factor (BDNF) leads to long-term potentiation (BDNF-LTP) of synaptic transmission at medial perforant path-->granule cell synapses in the rat dentate gyrus. Endogenous BDNF is implicated in the maintenance of high-frequency stimulation-induced LTP (HFS-LTP). However, the relationship between exogenous BDNF-LTP and HFS-LTP is unclear....

Regulation of glutamate reuptake occurs along with several forms of synaptic plasticity. These associations led to the hypothesis that regulation of glutamate uptake is a general component of plasticity at glutamatergic synapses. We tested this hypothesis by determining whether glutamate uptake is regulated during both the early phases (E-LTP) and late phases (L-LTP) of long-term potentiation (...

Long-term potentiation (LTP) is an activity-dependent increase in synaptic efficacy that is most studied in the hippocampus and that is considered a cellular substrate for learning and memory. Accepting the belief that the durability (persistence in time) of LTP is analogical to long-standing store of hippocampusdependent memories warrants the necessity for understanding the mechanisms underlyi...

Securing the resources is a most challenging task in digital era. Traditionally, password and ID card systems were used to provide security. Password cards can be stolen or hacked; overcome this drawback biometric are authenticate user access data resources. Biometric system uses physical behavioral characteristics of user. Biological person like face, fingerprint, iris, palm print, voice, hand...