Young leaves of Triticum aestivum is commonly known as Wheatgrass and has been widely used in the traditional system for the treatment of a variety of diseases. In this study we have used ninth day wheat grass methanolic extract of the shade dried drug for its anti-inflammatory & analgesic activities. . It was carried out using Carrageenan induced paw edema volume, Hot plate and Writhing respon...

A novel series of 3-(2-amino-6-pyrimidin-4-yl)-6-bromo-2H-chromen-2-one (5a-5j) were synthesized from 3-acetyl-6-bromo-2H-chromen-2-one (3). The structures of the synthesized compounds were elucidated by IR, H-NMR, C-NMR, and mass spectroscopic techniques. The synthesized compounds were screened for in-vivo analgesic activity at a dose of 20 mg/kg body weight. Among them, compounds 5a, 5b and 5...

The present study was designed to confirm the wide traditional use of treating pain with Salix canariensis, an endemic species of the Macaronesian region. The active compounds were identified. Pharmacological activities were explored in experimental animals by acetic acid-induced writhing, formalin and Levy's tests, and bioactive compounds were identified after a bio-guided fractionation of the...

Objective: Opuntia humifusa (O. humifusa) Raf. has been used for the prevention and treatment of rheumatoid arthritis, inflammation, and cancer. Our study was designed to unveil the anti-nociceptive and anti-inflammatory effects of the methanolic extract of O. humifusa Raf stem (OHS).  Material and Methods: The anti-nociceptive effect was measured by hot plate, acetic acid-induced writhing, and...

The ethanolic extract of Wedelia chinensis (EEWC) belonging to the family of Asteraceae was evaluated by hot plate and acetic acid induced writhing methods to assess its analgesic activity. The extract was also evaluated for its by using on carrageenan, mediators such as histamine and serotonin induced paw oedema, and cotton pellet induced granuloma tests for its effect on acute and chronic ...

methanolic extract of solanum trilobatum linn. (mest) belonging to the family of solanacea was evaluated by hot plate and acetic acid induced writhing methods to assess its analgesic activity. the extract was also evaluated for its anti-inflammatory activity by subjecting into carrageenan, and cotton pellet induced granuloma tests for its effect on acute and chronic phase inflammation models in...

The methanolic bark extract of Mimusops elengi was investigated for its possible analgesic and neuropharmacological activities on mice at the doses of 100mg/kg, 200mg/kg and 400mg/kg body weight. For the evaluation of analgesic activity, tail immersion and acetic acid induced writhing tests were used. The neuropharmacological activity of the extract was screened using hole cross and open field ...

The writhing number of a curve in Euclidean 3-space, introduced by Călugăreanu (1959-61) and named by Fuller (1971), is the standard measure of the extent to which the curve wraps and coils around itself; it has proved its importance for molecular biologists in the study of knotted duplex DNA and of the enzymes which affect it. The helicity of a vector field defined on a domain in Euclidean 3-s...