Neurons in the cingulate motor areas (CMA) have been shown to be involved in many aspects of sensorimotor behavior, although their role in motor learning has received less attention. Here, we recorded single-cell activity in the CMA of monkeys while they adapted reaching movements to different dynamic environments. Specifically, we analyzed CMA activity during normal reaching to visual targets ...

Bayesian model averaging (BMA) is the state of the art approach for overcoming model uncertainty. Yet, especially on small data sets, the results yielded by BMA might be sensitive to the prior over the models. Credal Model Averaging (CMA) addresses this problem by substituting the single prior over the models by a set of priors (credal set). Such approach solves the problem of how to choose the...

We studied the immunogenicity of a membrane fraction prepared from Candida albicans cells called C. albicans membrane antigen (CMA). The present study revealed that CMA immunization has antifungal activity in mouse models of systemic fungal infection. Immunization of mice by subcutaneous injections of CMA with incomplete Freund adjuvant induced resistance to infections caused not only by C. alb...

Employing the CMA (AAMA) to do clinical and administrative procedures in an ambulatory delivery setting is proving to be a cost-effective way of providing high-quality care. The CMA (AAMA) credential represents a Certified Medical Assistant (CMA) who has achieved certification through the American Association of Medical Assistants (AAMA). The CMA (AAMA) must graduate from an accredited postseco...

Chaperone-mediated autophagy (CMA) is a selective mechanism for the degradation of soluble cytosolic proteins in lysosomes. The limiting step of this type of autophagy is the binding of substrates to the lysosome-associated membrane protein type 2A (LAMP-2A). In this work, we identify a dynamic subcompartmentalization of LAMP-2A in the lysosomal membrane, which underlies the molecular basis for...

Parkinson's disease (PD), a complex neurodegenerative disorder, is pathologically characterized by the formation of Lewy bodies and loss of dopaminergic neurons in the substantia nigra pars compacta (SNc). Mitochondrial dysfunction is considered to be one of the most important causative mechanisms. In addition, dysfunction of chaperone-mediated autophagy (CMA), one of the lysosomal proteolytic ...

Chlormadinone acetate (CMA) and cyproterone acetate have been used in medicaltreatment of human benign prostatic hyperplasia (BPH) or prostatic carcinoma [2,3,8,9]. The atrophic effects of CMA on the prostate of rats and dogs have been previously reported from our laboratory[5,6]. Using spontaneous BPH dogs we found that immunostaining of androgen receptor (AR) in both epithelial and stromal fi...

A code-aided constant modulus algorithm (CMA) based approach is presented for blind detection of asynchronous short-code DS-CDMA (direct sequence code division multiple access) signals in intersymbol interference (ISI)/multipath channels. Only the spreading code of the desired user is assumed to be known; its transmission delay may be unknown. A linear equalizer is designed by minimizing the Go...

The shape of the main arc formed by the Canis Major clouds has been suggested to result from a supernova explosion possibly triggering the recent star formation activity. The presence of dozens of OB stars and reflection nebulae forms the CMa OB1/R1 associations. More than a hundred emission line stars are found in this region, including the famous Z CMa, a binary system containing a Herbig Be ...