High vitamin A ingestion or high serum retinol have been postulated to increase the risk of fractures and osteoporosis by reduced bone mineral density (BMD). Retinol is carried and transported to the tissues bound to retinol binding protein 4 (RBP4) and transthyretin (TTR). The relationships between retinol, retinol transport protein, retinol binding protein 4 (RBP4) and transthyretin (TTR) and...

The unique cell cycle dynamics of meiosis are controlled by layers of regulation imposed on core mitotic cell cycle machinery components by the program of germ cell development. Although the mechanisms that regulate Cdk1/Cyclin B activity in meiosis in oocytes have been well studied, little is known about the transacting factors responsible for developmental control of these factors in male gam...

PCR-RFLP was applied to a commercial crossbred pig population in order to investigate the association between polymorphism (SNP) of Retinol-binding protein 4 (RBP4) gene and reproductive performance. 400 sows were genotyped and 2000 records of reproductive traits were used in order to retrieve information about the allele frequencies and the association of the RBP4 gene with main reproductive c...

UNLABELLED Aims/Introduction:  Visceral obesity has been suggested to be an independent risk factor for cardiovascular disease (CVD); the role of adipokines in the risk for CVD is less clear. Aim of this study was to investigate the relationship between parameters of visceral obesity and index of CVD risk factors. MATERIALS AND METHODS   A cross-sectional analysis of healthy males (n = 116) a...

OBJECTIVE The investigation of the association between retinol-binding protein 4 (RBP4) and lipoproteins in subjects with hypertriglyceridemia. DESIGN Forty-six obese or overweight hypertriglyceridemic patients were studied at baseline and 20 of them underwent a hypocaloric low-fat diet for 3 months. RESULTS Plasma RBP4 levels were positively correlated with serum triglycerides (TG) in the ...

the aim of this study was to examine the effect of 12 weeks of concurrent training on rbp4 andinsulin resistance levels in obese middle-age men. for this purpose, 20 obese middle-age men voluntarily participated in this study and were assigned to concurrent training group (n=10, mean age 51.2 ± 2.25 yr and bmi 31.44 ± 0.81 kg/m²) and control group (n=10, mean age 50.3 ± 2.11 yr and bmi 30.32 ± ...

CONTEXT Women with previous gestational diabetes mellitus (pGDM) are at high risk of developing type 2 diabetes mellitus in the future. The role of adipokines in women with pGDM has not been established. OBJECTIVE We investigated whether circulating adipokine concentration is associated with abnormal glucose homeostasis in women with pGDM. DESIGN, SETTING, PATIENTS, AND MAIN OUTCOME MEASURES:...

Retinol-binding protein 4(RBP4), and irisin originally described as an adipocyte-specific hormone, has been suggested to be important link between obesity, insulin resistance diabetes. To test the hypothesis that RBP4, concentrations will higher in obese subject than normal weight. A total of 176 individuals were evaluated, which divided into three groups according BMI. Group I (Normal Weight g...

BACKGROUND The prevalence of obesity and its related comorbidities, such as fatty liver, in children is increasing worldwide mostly due to changes in diet and life-style. Many serological markers have been suggested for screening of fatty liver but investigations for finding more reliable factors are still in progress. OBJECTIVES This study aimed to investigate the correlation between the lev...