Total flavonoids are the main pharmaceutical components of Trollius chinensis Bunge, and orientin and vitexin are the monomer components of total flavonoids in Trollius chinensis Bunge. In this study, an aged mouse model was established through intraperitoneal injection of D-galactose for 8 weeks, followed by treatment with 40, 20, or 10 mg/kg orientin, vitexin, or a positive control (vitamin E...

Plant metabonomic analysis is essential for understanding plant systems responses to osmotic stresses. To understand the comprehensive metabolic responses of Salvia miltiorrhiza Bunge (SMB) to continuous and exhaustive water depletion, we characterized the SMB metabonomic variations induced by three different drying processes using the combined NMR and LC-DAD-MS method. NMR results showed that ...

Salvia miltorrhiza Bunge is a traditional Chinese medicine and has long been used for treating liver and heart diseases in China. Salvianic acid A is the main active component of Salvia miltorrhiza Bunge. In the present study, the ability of salvianic acid A in scavenging free radicals, inhibiting lipid peroxidation and mitochondrial membrane permeability transition, as well as respiration and ...

Astragalus membranaceus is an important medicinal plant in Asia. Several of its varieties have been used interchangeably as raw materials for commercial production. High resolution genetic markers are in urgent need to distinguish these varieties. Here, we sequenced and analyzed the chloroplast genome of A. membranaceus (Fisch.) Bunge var. mongholicus (Bunge) P.K. Hsiao using the next generatio...

Salvia miltiorrhiza Bunge has been reported to possess excellent antifibrotic activity. In this study, we have investigated the effect and mechanism of tanshinone IIA (Tan-IIA), salvianolic acid A (Sal-A) and salvianolic acid B (Sal-B), the important active compounds of Salvia miltiorrhiza Bunge, on areca nut extract (ANE)-induced oral submucous fibrosis (OSF) in vitro. Through human procollage...

The study focuses on the first position held by pharmacologist Hans Horst Meyer (1853–1939) 1 as a professor of pharmacology, dietetics, and history medicine at University Dorpat (today, Tartu University, Estonia) from 1882 to 1884. is known founder pharmacology an independent academic discipline in Vienna (Austria). 2 He competed with well-known physiologist Gustav Piers Alexander von Bunge (1...

Astragalus roots from Astragalus membranaceus Bunge or Astragalus membranaceus var. mongholicus (Bunge) Hsiao are among the most popular traditional medicinal plants due to their diverse therapeutic uses based on their tonic, antinephritic, immunostimulant, hepatoprotectant, diuretic, antidiabetic, analgesic, expectorant and sedative properties. Currently, the herb is produced or cultivated in ...

At present the view is commonly accepted that hippuric acid is produced chiefly by the kidney in most animals and exclusively by that organ in the dog. This conclusion is based largely on the well known work of Bunge and Schmiedeberg (1) who were able to dem0nstrat.e that hippuric acid was formed when blood containing benzoic acid and glycine was perfused through dog kidney. Furthermore, they f...

Patrinia heterophylla Bunge, Caprifoliaceae, is a traditional Chinese medicine that has been used for cancer therapy. In our study, a panel of human cancer cells was treated with extract of Patrinia heterophylla Bunge. (PHEB), MTT study showed that PC-3 Human prostate adenocarcinoma was the most responsive (IC50 9.21±0.32 μg/mL) one to cell growth inhibition, the further study also demonstrated...

En la presente editorial reescribimos el relato acerca de los modelos investigación científica que revista desarrolla. Basados en Mario Bunge y Sampieri et al., presentamos sintéticamente metodología métodos se fundamentan ella. De esta forma, pretendemos facilitar camino a investigadores uso intencionado diseños metodológicos permiten al diseño gráfico fortalecer su anclaje científico mejorar ...