CONTEXT Beginning in 1957, patients have been described with localized alopecia characterized histopathologically by mucin deposition within hair follicles (follicular mucinosis [FM]). At least 2 distinct diagnostic entities have been proposed: one occurring in children and young adults without association with other diseases ("idiopathic" FM), the other occurring in elderly patients and associ...

BACKGROUND Onychomycosis is a type of fungal infection that accounts for over 50% of all onycopathies. Some authors consider superficial mycosis the most difficult to be treated. Very few studies have been carried out in order to assess the epidemiology of onychomycosis in Brazil. OBJECTIVE To describe the epidemiological profile of onychomycosis in Brazilian dermatology offices and to assess...

background & aim: a meta-analysis refers to the statistical synthesis of results from a series of studies and has been used to estimate pooled prevalence of human diseases. in this study, we review some statistical issues regarding the meta-analysis of the prevalence of human diseases such as statistical software and programs, transformations of prevalence rate, assessment of heterogeneity, and...

micrornas (mirnas) are short rna molecules which bind to target mrnas, resulting in translational repression and gene silencing and are found in all eukaryotic cells. approximately 2200 mirna genes have been reported to exist in the mammalian genome, from which over 1000 belong to the human genome. many major cellular functions such as development, differentiation, growth, and metabolism are kn...

A patient with advanced mycosis fungoides developed neurologic and respiratory symptoms and signs following multiple courses of chemotherapy and radiotherapy. Various repeated diagnostic procedures--including cranial computerized tomography and fiberoptic bronchoscopy with transbronchial lung biopsy--failed to demonstrate an unusual involvement of the brain and lungs by mycosis fungoides. Radio...

Paracoccidioidomycosis (PCM) is a deep mycosis caused by the Paracoccidioides brasiliensis fungus. The primary disease affects the lungs, and can spread to other organs and tissues, creating secondary lesions. The most frequent systemic signs and symptoms are cough, lung secretion and weight loss. When present, the oral lesions are characterized by red and punctual micropapulae, settled amidst ...

Sir, Demodex mites are common ectoparasites of human skin (1). Two species, Demodex folliculorum and the smaller D. brevis, inhabit the human pilosebaceous unit and are found in individuals of all ages except neonates. They inhabit almost every area of human skin but show a predilection for the face, especially the nose and nasolabial folds. Cases in which demodicidosis developed on other sites...

conclusions patients who regularly use the local saunas had poor personal hygiene and greasy skin, and were more suspected to tinea versicolor infection. results the disease was more prevalent in 21-40 years old age group in both genders. the most infected anatomical regions were posterior surface, the body trunk (shoulder, supra scapula and lumbar region), anterior thorax and abdomen, respecti...