Hindbrain glucagon-like peptide 1 (GLP-1) neurons project to numerous forebrain areas, including the lateral septum (LS). Using a fluorescently labeled GLP-1 receptor (GLP-1R) agonist, Exendin 4 (Ex4), we demonstrated GLP-1 receptor binding throughout the rat LS. We examined the feeding effects of Ex4 and the GLP-1R antagonist Exendin (9-39) (Ex9) at doses subthreshold for effect when delivered...

The inheritance of stress responsiveness (line effects and combining abilities) was phenotypically studied in progeny from diallel crosses of randombred (RB) quail and quail selected for exaggerated (high stress, HS) or reduced (low stress, LS) plasma corticosterone (CS) response to brief immobilization. The three genotypes were crossed in a 3 x 3 factorial arrangement of treatments that allowe...

Noninvasive screening for liver cirrhosis in patients addicted to drugs or alcohol has been a continuing problem in internal and addictive medicine. This has dramatically changed with the recent introduction of transient elastography (Fibroscan) to directly measure liver stiffness (LS). This novel technique is expanding rapidly around the globe since it allows the diagnosis of liver cirrhosis i...

Copyright: © 2013 Wang Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Lynch Syndrome (LS), or Hereditary Non-Polyposis Colon Cancer (HNPCC), is caused by a germline mutation in one of several DNA Mi...