BACKGROUND Acute tandem cervical dissecting internal carotid artery (ICA) occlusion and intracranial embolic middle cerebral artery (MCA) occlusion can be devastating, and the optimal treatment strategy for this condition has not been established yet. CASE DESCRIPTION A 45-year-old male presented with aphasia and right hemiparesis preceded by neck pain. Computed tomography showed a high-densi...

Maurocalcine (MCa), a 33 amino acid toxin obtained from scorpion venom, has been shown to interact with the isolated skeletal-type ryanodine receptor (RyR1) and to strongly modify its calcium channel gating. In this study, we explored the effects of MCa on RyR1 in situ to establish whether the functional interaction of RyR1 with the voltage-sensing dihydropyridine receptor (DHPR) would modify t...

Aphasia is an acquired language impairment caused by damage in the regions of brain that support language. The Main Concept Analysis (MCA; Kong, 2016b) a published formal assessment battery allows quantification presence, accuracy, completeness, and efficiency content spoken discourse produced persons with aphasia (PWA). It utilizes sequential picture description task (with four sets pictures) ...

Background: The use of middle cerebral artery (MCA) angioplasty compared with drug therapy has been controversial. Few studies have reported the correlations between cognitive function improvement and MCA angioplasty. This study aimed to explore neurocognitive after in patients stenosis (MCAS) objective ischemia.

Meerkat Clan Algorithm (MCA) is a nature-based metaheuristic algorithm which imitates the intelligent behavior of meerkat animal. This paper presents an improvement on MCA based chaotic map and crossover strategy (MCA-CC). These two strategies increase diversification intensification proposed boost searching ability to find more quality solutions. The 0-1 knapsack problem was solved by basic im...

Although postnatal maturation potently modulates agonist-induced cerebrovascular contractility, its effects on the mechanisms mediating cerebrovascular myogenic tone remain poorly understood. Because the regulation of calcium influx and myofilament calcium sensitivity change markedly during early postnatal life, the present study tested the general hypothesis that early postnatal maturation inc...

PURPOSE The aim of the present study was to investigate the diagnostic potential of contrast-enhanced transcranial color-coded real-time sonography (CE-TCCS) in otherwise ultrasound-refractory acute stroke patients with an ischemia in the territory of the middle cerebral artery (MCA). Furthermore, correlations of CE-TCCS findings with clinical, angiographic, and CT results were investigated. ...