نتایج جستجو برای: آنالیز in silico

تعداد نتایج: 17016896  

Journal: :journal of cell and molecular research 0
farzaneh khaloiee poneh pourfarzam iraj rasooli jafar amani shahram nazarian seyed latif mousavi

shigella and escherichia belong to the enterobacteriaceae family which are the cause for most of the diarrheal cases in the world. shigella can cause bacterial dysenteries and shigellosis. one of the most effective proteins for pathogenesis is invasion plasmid antigen c (ipac). other bacteria like enterotoxogenic (etec), enterohemorrhagic (ehec), and e.coli can also cause diarrhea and produce i...

Journal: :Regulatory Toxicology and Pharmacology 2020

Journal: :iranian journal of microbiology 0
abbas abdollahi department of microbiology, kerman university of medical sciences, kerman, iran shahla mansouri department of microbiology, kerman university of medical sciences, kerman, iran jafar amani applied microbiology research center, baqiyatallah university of medical sciences, tehran, iran mahdi ramandi fasihi 3molecular biology research center, baqiyatallah university of medical sciences, tehran, iran mohammad moradi department of microbiology, kerman university of medical sciences, kerman, iran

background and objectives: brucellosis is an important health problem in developing countries and no vaccine is available for the prevention of infection in humans. because of clinically infectious diseases and their economic consequences in human and animals, designing a proper vaccine against brucella is desirable. in this study, we evaluated the immune responses induced by a designed recombi...

Journal: :iranian journal of microbiology 0
a madhour department of microbiology, university of kaiserslautern, paul-ehrlich str. 23, d-67663 kaiserslaute p maurer department of microbiology, university of kaiserslautern, paul-ehrlich str. 23, d-67663 kaiserslaute r hakenbeck department of microbiology, university of kaiserslautern, paul-ehrlich str. 23, d-67663 kaiserslaute

background and objectives: streptococcus pneumoniae, a major human pathogen, is closely related to the commensal species s. mitis and s. oralis. s. pneumoniae surface proteins are implicated in virulence and host interaction of this species, but many of them have recently been detected in s. mitis b6 in silico. we tested for the presence of such genes usinga set of eight s. mitis and eleven s. ...

2007
Robert M. Kuhn Donna Karolchik Ann S. Zweig Heather Trumbower Daryl J. Thomas Archana Thakkapallayil Charles W. Sugnet Mario Stanke Kayla E. Smith Adam C. Siepel Kate R. Rosenbloom Brooke L. Rhead Brian J. Raney Andy Pohl Jakob Skou Pedersen Fan Hsu Angela S. Hinrichs Rachel A. Harte Mark Diekhans Hiram Clawson Gill Bejerano Galt P. Barber Robert Baertsch David Haussler W. James Kent

The University of California, Santa Cruz (UCSC) Genome Browser website (http://genome.ucsc.edu/) provides a large database of publicly available sequence and annotation data along with an integrated tool set for examining and comparing the genomes of organisms, aligning sequence to genomes, and displaying and sharing users' own annotation data. As of September 2009, genomic sequence and a basic...

Journal: :Nucleic Acids Research 2006
Angela S. Hinrichs Donna Karolchik Robert Baertsch Galt P. Barber Gill Bejerano Hiram Clawson Mark Diekhans Terrence S. Furey Rachel A. Harte Fan Hsu Jennifer Hillman-Jackson Robert M. Kuhn Jakob Skou Pedersen Andy Pohl Brian J. Raney Kate R. Rosenbloom Adam C. Siepel Kayla E. Smith Charles W. Sugnet A. Sultan-Qurraie Daryl J. Thomas Heather Trumbower R. J. Weber M. Weirauch Ann S. Zweig David Haussler W. James Kent

The University of California Santa Cruz Genome Browser Database (GBD) contains sequence and annotation data for the genomes of about a dozen vertebrate species and several major model organisms. Genome annotations typically include assembly data, sequence composition, genes and gene predictions, mRNA and expressed sequence tag evidence, comparative genomics, regulation, expression and variation...

2015
Pauline Mazzocco Jérôme Honnorat François Ducray Benjamin Ribba

BACKGROUND We previously developed a mathematical model capturing tumor size dynamics of adult low-grade gliomas (LGGs) before and after treatment either with PCV (Procarbazine, CCNU, and Vincristine) chemotherapy alone or with radiotherapy (RT) alone. OBJECTIVE The aim of the present study was to present how the model could be used as a simulation tool to suggest more effective therapeutic s...

Journal: :iranian journal of basic medical sciences 0
ahmad mohammadi-farani pharmaceutical sciences research center, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran department of pharmacology, toxicology and medical services, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran nasibeh abdi students research committee, kermanshah university of medical sciences, kermanshah, iran department of medicinal chemistry, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran alireza moradi neurobiomedical research center, yazd shahid sadoughi university of medical sciences, yazd, iran alireza aliabadi pharmaceutical sciences research center, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran

objective(s): alzheimer’s disease (ad) as progressive cognitive decline and the most common form of dementia is due to degeneration of the cholinergic neurons in the brain. therefore, administration of the acetylcholinesterase (ache) inhibitors such as donepezil is the first choice for treatment of the ad. in the present study, we focused on the synthesis and anti-cholinesterase evaluation of n...

Journal: :Nucleic acids research 2004
Kirill Rotmistrovsky Wonhee Jang Gregory D. Schuler

'Electronic PCR' (e-PCR) refers to a computational procedure that is used to search DNA sequences for sequence tagged sites (STSs), each of which is defined by a pair of primer sequences and an expected PCR product size. To gain speed, our implementation extracts short 'words' from the 3' end of each primer and stores them in a sorted hash table that can be accessed efficiently during the searc...

2014
Omri Wolk Riad Agbaria Arik Dahan

The main objective of this work was to investigate in-silico predictions of physicochemical properties, in order to guide oral drug development by provisional biopharmaceutics classification system (BCS). Four in-silico methods were used to estimate LogP: group contribution (CLogP) using two different software programs, atom contribution (ALogP), and element contribution (KLogP). The correlatio...

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