نتایج جستجو برای: γ spectrometry
تعداد نتایج: 171930 فیلتر نتایج به سال:
Background: Lead is a highly toxic metal of great public health importance. Objectives: This cross-sectional study was conducted to evaluate the kidney and liver function status markers oxidative stress among lead recycling factory workers in Anambra State, Nigeria. Methods: A total 82 subjects (41 experimental 41 control subjects) aged 20-60 years were recruited this study. levels whole blood ...
Endoplasmic reticulum (ER) α-1, 2-mannosidase (ERManI) contributes to ER-associated protein degradation (ERAD) by initiating the formation of degradation signals on misfolded N-linked glycoproteins. Despite its inferred intracellular location, we recently discovered that the mammalian homologue is actually localized to the Golgi complex. In the present study, the functional role of Golgi-situat...
The upstream Gγ-globin cAMP-response element (G-CRE) plays an important role in regulating Gγ-globin expression through binding of ATF2 and its DNA-binding partners defined in this study. ATF2 knockdown resulted in a significant reduction of γ-globin expression accompanied by decreased ATF2 binding to the G-CRE. By contrast, stable ATF2 expression in K562 cells increased γ-globin transcription ...
The amyloid β-protein (Aβ) deposited in Alzheimer’s disease (AD) is a normally secreted proteolytic product of the amyloid β-protein precursor (APP). Generation of Aβ from the APP requires two sequential proteolytic events: an initial β-secretase cleavage at the amino terminus of the Aβ sequence followed by γ-secretase cleavage at the carboxyl terminus of Aβ. We describe the development of a ro...
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