نتایج جستجو برای: β2 glycoprotein i

تعداد نتایج: 1125751  

Journal: :Biochemical Journal 2005

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Journal: :Kidney International 2012

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Journal: :Arthritis & Rheumatism 2011

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Journal: :The Journal of Immunology 2010

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2011
JYOTI SINGH

The stability constants of complexes formed by Thallium (I) with Serine and Leucine have been investigated in aqueous medium, the complex with metal Serine as 1:1, 1:2 and complexes of the Tl(I) with Leucine as 1:1, 1:2 have been reported. The values of formation constant of Serine are log β1 = 2.1760, log β2 = 3.85325 at 308K and log β1 = 1.9030, log β2 = 3.6739 at 318K and complexes of Tl(I) ...

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Journal: :Journal of Clinical Investigation 2002

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Journal: :The Journal of Immunology 2017

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Journal: :Blood 2012
Kristi L Allen Fabio V Fonseca Venkaiah Betapudi Belinda Willard Jainwei Zhang Keith R McCrae

Antiphospholipid Abs (APLAs) are associated with thrombosis and recurrent fetal loss. These Abs are primarily directed against phospholipid-binding proteins, particularly β(2)GPI, and activate endothelial cells (ECs) in a β(2)GPI-dependent manner after binding of β(2)GPI to EC annexin A2. Because annexin A2 is not a transmembrane protein, the mechanisms of APLA/anti-β(2)GPI Ab-mediated EC activ...

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2017
Luis R Lopez Ignacio Garcia-De La Torre Eiji Matsuura Paul RJ Ames

Diabetes mellitus (DM) is the fifth deadliest disease in the United States with an annual economic cost estimated over $100 billion. Cardiovascular disease (CVD) represents the most life threatening consequence of DM accounting for the death of up to 65% of DM patients. Aggressive efforts aimed at treating and controlling the classic CVD risk factors over the last few decades have brought along...

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2011
Miyuki Bohgaki Masaki Matsumoto Tatsuya Atsumi Takeshi Kondo Shinsuke Yasuda Tetsuya Horita Keiichi I Nakayama Fumihiko Okumura Shigetsugu Hatakeyama Takao Koike

Antiphospholipid syndrome (APS) is characterized by thrombosis and the presence of antiphospholipid antibodies (aPL) that directly recognizes plasma β(2)-glycoprotein I (β(2) GPI). Tissue factor (TF), the major initiator of the extrinsic coagulation system, is induced on monocytes by aPL in vitro, explaining in part the pathophysiology in APS. We previously reported that the mitogen-activated p...

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  • " +i+ "
    • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->