background: sustainable and commercial production of secondary metabolites is a critical issue when dealing with its clinical application. efforts are still being made to look for biotic or abiotic elicitors with more efficient and universal effects on the improvement of secondary metabolites. objective: in order to evaluate the suitability of different biotic elicitors on p. harmala l. cell su...

beta-Carboline alkaloids are natural products widely distributed in plants and also found in alcoholic beverages, well-cooked foods and tobacco smoke. Various authors have reported genotoxic activities of several carboline in prokaryotic and eukaryotic cells that have been attributed to their abilities to intercalate into DNA. But studies on the genotoxic and on the cytotoxic potencies in human...

Concern about the side effects of liver cancer treatment has driven studies on anticancer to find compounds from plants that can act as chemotherapy. The activity Chromolaena odorata against colorectal cancer, lung leukemia, cervical breast and been proven. However, this plant’s mechanism inhibit cell growth is still undetermined. This study aims investigate C. HepG2 cells. Extraction leaves wa...

beta-Carbolines are tricyclic nitrogen heterocycles formed in plants and animals as Maillard reaction products between amino acids and reducing sugars or aldehydes. They are being detected increasingly in human tissues, and their physiological roles need to be understood. Two beta-carboline carboxylates have been reported to accumulate in the human eye lens. We report here on the identification...