The application of nanoparticle drug formulations, such as nanoliposomal doxorubicin (Doxil), is increasingly integrated in clinical cancer care. Despite nanomedicine's remarkable potential and growth over the last three decades, its clinical benefits for cancer patients vary. Here we report a non-invasive quantitative positron emission tomography (PET) nanoreporter technology that is predictiv...

The title dimeric zirconium complex, [Zr(2)(C(20)H(24))(2)S(2)]·C(7)H(8), was obtained from the reaction of (ebthi)Zr(η(2)-Me(3)Si-C(2)-SiMe(3)) [ebthi is rac-1,2-bis-(η(5)-4,5,6,7-tetra-hydro-inden-1-yl)ethane] and S=C=N-ada (ada = adamantan-1-yl) along with the formation of the isonitrile C N-ada. Each Zr(IV) atom is coordinated by the sterically hindered ebthi ligand and two μ-sulfide ligand...

In order to control of the calcium phosphate precipitation of Ti in body fluid, which might result in assimilated bone re-facture during removal operation of implanted devices such as femoral nails and bone screws after healing, vacuum vapor deposition of Zr on Ti Substrate was carried out. The calcium phosphate precipitation was evaluated through the immersion test into the Hanks’ solution. Sc...

A co-impregnation method was applied to the Ni/Zr-HMS/HZSM-5 catalyst (with various amounts of zirconium) during the hydrogenation of benzene. The physicochemical properties of the prepared nickel catalyst were characterized using X - ray diffraction, X - ray fluorescence, Fourier transform infrared spectroscopy, ultraviolet-visible diffuse reflectance spectroscopy, temperature-programmed desor...

Synthesis and characterisation of new permethylpentalene (Pn*) zirconium bis(amido) Pn*Zr cyclopentadienyl mono(amido) complexes their reactivity with carbon dioxide.

Mixed leukocyte (white blood cells [WBCs]) trafficking using positron emission tomography (PET) is receiving growing interest to diagnose and monitor inflammatory conditions. PET, a high sensitivity molecular imaging technique, allows precise quantification of the signal produced from radiolabelled moieties. We have evaluated a new method for radiolabelling WBCs with either zirconium-89 ((89) Z...

The new binuclear phenoxyiminato zirconium complex {1,7-(O)2C10H4-2,7-[CH=N(2,6-iPr2C6H3)]2}Zr2Cl6(THF)2 (FI2-Zr2) polymerizes ethylene with greater activity (approximately 8x) than the mononuclear analogue. Also, this catalyst produces high molecular weight ethylene + 1-hexene copolymers, while the mononuclear analogue yields only traces of copolymer under identical conditions. This ability to...

Reaction of (ClMe2SiC5H4)2ZrCl2 (1) with K (Na) in liquid ammonia/toluene at -78 °C gave the ansa-zirconocene dihydride [{HN(SiMe2C5H4)2Zr(μH)H}2] (3). Alternatively, treatment of (MeC5H4)2ZrCl2 (2) with K (Na) or NaNH2 in liquid ammonia/toluene produced the zirconium cluster [{(MeC5H4)Zr}5(μ5-N)(μ3-NH)4(μ-NH2)4] (4). The reaction of 2 with NaNH2 in THF led also to the formation of 4.