نتایج جستجو برای: zinc metaborate

تعداد نتایج: 73603  

Journal: :The Journal of infectious diseases 2014
Hanna Jarva

When we think about trace elements and bacterial virulence, iron is usually the first metal that comes up. Zinc, although often forgotten, is the second most abundant trace element, after iron, in humans. Plasma concentrations of zinc range between 12 and 16 μM, and practically all zinc is bound to albumin or other proteins [1]. Zinc is found at low levels on mucosal surfaces; in sputum and bro...

Journal: :The Journal of nutrition 2011
Meika Foster Dale Hancock Peter Petocz Samir Samman

The zinc transporter (ZnT; SLC30) and Zrt- and Irt-like protein (Zip, SLC39) zinc transporter families are integral to the maintenance of intracellular zinc concentrations. Few studies have examined the expression patterns of zinc transporter genes in human primary tissues. This study investigated the expression levels of a range of zinc transporter mRNA in the peripheral blood mononuclear cell...

Journal: :Environmental microbiology 2013
Chee Kent Lim Karl A Hassan Anahit Penesyan Joyce E Loper Ian T Paulsen

Zinc is an important nutrient but can be lacking in some soil environments, influencing the physiology of soil-dwelling bacteria. Hence, we studied the global effect of zinc limitation on the transcriptome of the rhizosphere biocontrol strain Pseudomonas protegens Pf-5 (formerly Pseudomonas fluorescens). We observed that the expression of the putative zinc uptake regulator (Zur) gene was upregu...

2018
Lasse Kjellerup Anne-Marie L. Winther Duncan Wilson Anja T. Fuglsang

Zinc is an essential micronutrient, required for a range of zinc-dependent enzymes and transcription factors. In mammalian cells, zinc serves as a second messenger molecule. However, a role for zinc in signaling has not yet been established in the fungal kingdom. Here, we used the intracellular zinc reporter, zinbo-5, which allowed visualization of zinc in the endoplasmic reticulum and other co...

2017
Seung-Hwan Choi Kang-Lok Lee Jung-Ho Shin Yoo-Bok Cho Sun-Shin Cha Jung-Hye Roe

In most bacteria, zinc depletion is sensed by Zur, whereas the surplus is sensed by different regulators to achieve zinc homeostasis. Here we present evidence that zinc-bound Zur not only represses genes for zinc acquisition but also induces the zitB gene encoding a zinc exporter in Streptomyces coelicolor, a model actinobacteria. Zinc-dependent gene regulation by Zur occurs in two phases. At s...

2002

Zinc is an essential element in people’s diet. Too little zinc can cause health problems, but too much zinc is harmful. The U.S. Recommended Dietary Allowance (U.S. RDA) for zinc is 5 15 milligrams a day for humans. Not enough zinc in one’s diet can result in a loss of appetite, a decreased sense of taste and smell, slow wound healing and skin sores, or a damaged immune system. Young men who do...

2015
Daniel Y. Zhang Maria Azrad Wendy Demark-Wahnefried Christopher J. Frederickson Stephen J. Lippard Robert J. Radford

Small-molecule fluorescent sensors are versatile agents for detecting mobile zinc in biology. Capitalizing on the abundance of validated mobile zinc probes, we devised a strategy for repurposing existing intensity-based sensors for quantitative applications. Using solid-phase peptide synthesis, we conjugated a zinc-sensitive Zinpyr-1 derivative and a zinc-insensitive 7-hydroxycoumarin derivativ...

1998
Friedhelm Brinkhaus Jim Mann Cris Zorich John A. Greaves

Supplementation with zinc improves overall health, productivity and performance of production animals such as poultry, swine and dairy animals as measured by body weight increase, final body weight or feed/gain ratios. Reports on beneficial effects of zinc supplementation are fewer for companion animals. Lowe et al. (1994 a) reported more hair growth with higher zinc content in dogs upon supple...

2013
Jim Geiser Robert C. De Lisle Glen K. Andrews

BACKGROUND ZIP5 localizes to the baso-lateral membranes of intestinal enterocytes and pancreatic acinar cells and is internalized and degraded coordinately in these cell-types during periods of dietary zinc deficiency. These cell-types are thought to control zinc excretion from the body. The baso-lateral localization and zinc-regulation of ZIP5 in these cells are unique among the 14 members of ...

2007
Naima Layachi

The aim of this study was to investigate the beneficial effect of vitamin E supplementation on zinc deficiency in experimental diabetes. Male alloxan-diabetic Wistar, albino rats of 10 weeks of age were divided into three groups. The first group received a diet containing 54 mg zinc/kg (adequate zinc group, AZ), the second group received a diet containing 1mg zinc/kg (zinc deficient group, ZD),...

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