There are six members of the tubulin superfamily in eukaryotes. Alpha- and beta-tubulin form a heterodimer that polymerizes to form microtubules, and gamma-tubulin nucleates microtubules as a component of the gamma-tubulin ring complex. Alpha-, beta-, and gamma-tubulin are conserved in all eukaryotes. In contrast, delta- and epsilon-tubulin are conserved in many, but not all, eukaryotes and are...

This paper generalizes Bass’ work on zeta functions for uniform tree lattices. Using the theory of von Neumann algebras, machinery is developed to define the zeta function of a discrete group of automorphisms of a bounded degree tree. The main theorems relate the zeta function to determinants of operators defined on edges or vertices of the tree. A zeta function associated to a non-uniform tree...

Generation of superoxide anion by the multiprotein complex NADPH phagocyte oxidase is accompanied by extensive phosphorylation of its 47-kDa protein component, p47(phox), a major cytosolic component of this oxidase. Protein kinase C zeta (PKC zeta), an atypical PKC isoform expressed abundantly in human polymorphonuclear leukocytes (PMN), translocates to the PMN plasma membrane upon stimulation ...

The nucleus contains diacylglycerol kinases (DGKs), i.e., the enzymes that, by converting diacylglycerol (DG) into phosphatidic acid, terminate DG-dependent events. It has been demonstrated that nuclear DGK-zeta interferes with cell cycle progression. We previously reported that nuclear DGK-zeta expression increased during myogenic differentiation, whereas its down-regulation impaired different...

Fouling by natural organic matter like humic substances is one of the major factors limiting the application of microporous membranes for water production. The charge of the pore surface of membrane, which can be characterized by the streaming potential(SP) measurement as the apparent zeta potential ζ obs, has a large effect on its fouling performance. However the relationship between the fouli...

The zeta-family dimers (zeta, eta, and gamma) are a group of structurally and functionally related proteins that are expressed in developing thymocytes and function as signal transducing subunits of the T cell antigen receptor (TCR) and certain Ig Fc receptors. Zeta, eta, and gamma each contain one or more copies of a conserved tyrosine-based activation motif (TAM) that is known to be required ...

The relationship between the structure of the T cell antigen receptor (TCR)-CD3 complex and development of NK1.1+ T cells was investigated. The TCR complex of freshly isolated NK1.1+ TCR-alpha/beta+ thymocytes contained CD3 zeta homodimers and CD zeta-FcR gamma heterodimers, whereas that of the majority of NK1.1- T cells did not contain FcR gamma. The function of CD3 zeta and FcR gamma in the d...

This paper summarizes theory, experimental techniques, and the reported data pertaining to the zeta potential of silica and silicon with attention to use as microfluidic substrate materials, particularly for microchip chemical separations. Dependence on cation concentration, buffer and cation type, pH, cation valency, and temperature are discussed. The Debye-Hückel limit, which is often correct...

All plane curves of degree less than 7 with coefficients in F2 are examined for curves with a large number of Fq rational points on their smooth model, for q = 2,m = 3, 4, ..., 11. Known lower bounds are improved, and new curves are found meeting or close to Serre’s, Lauter’s, and Ihara’s upper bounds for the maximal number of Fq rational points on a curve of genus g.