Transdermal drug delivery systems are polymeric patches containing dissolved or dispersed drugs that deliver therapeutic agents at a constant rate to the human body. Matrix type transdermal patches were prepared using alprazolam as a model drug and employing the combinations of chitosan-polyvinyl alcohol (CS-PVA) cross linked with Maleic anhydride. The transdermal patches were evaluated for the...

Additional Index Words: rate constant, zero-order reaction, firstorder reaction, submerged soil, available carbon. A theoretical analysis of denitrification occurring in submerged soil in a test tube, when assumed to be a zero-order reaction with available ———————————————————— organic carbon nonlimiting, appears to be a first-order reaction if the __ , , , , c effects of diffusion are neglected...

This study aimed to investigate the oxidation profile of wheat germ oil extracted from raw during stabilization with microwave (MW) treatment, and kinetics parameters (free fatty acids (FFA), peroxide value (PV), thiobarbituric acid (TBA), α-tocopherol, lipase (LA) lipoxygenase (LOX) enzymes activities) under different storage conditions. For stabilizing germ, MW was treated at 700 W for three ...

Kinetics of oxidation of glycine (gly) and valine (val) by N-bromosuccinimide (NBS) using chloro complex of Rh(III) in its nano-concentration range as homogeneous catalyst have been investigated at 35 C . The reaction shows first order kinetics with respect to NBS and Rh(III) in the oxidation of both the amino acids. The first order kinetics with respect to amino acid obtained at its lower conc...

Adsorption of water on a thin silica film grown on a Mo(112) single crystal was studied by temperatureprogrammed desorption, infrared reflection absorption spectroscopy, and photoelectron spectroscopy using synchrotron radiation. Water does not dissociate on the defect-free oxygen-terminated silica surface. In contrast to adsorption at 100 K, where water follows a zero-order desorption kinetics...

We report here the design, development and performance of a novel formulation of liposome- encapsulated glucocorticoids (GCs). A highly efficient (>90%) and stable GC encapsulation was obtained based on a transmembrane calcium acetate gradient driving the active accumulation of an amphipathic weak acid GC pro-drug into the intraliposome aqueous compartment, where it forms a GC-calcium precipita...

The purpose of the present research work was to observe the effects of drug solubility on their release kinetics of water soluble verpamil hydrochloride and insoluble aceclofenac from hydrophilic polymer based matrix formulations. Matrix formulations were prepared by the direct compression method. The formulations were evaluated for various physical parameters. Along with the dynamics of water ...

Conventional kinetic analysis of the reactions of nitromethane (NM), nitroethane (NE) and 2-nitropropane (2-NP) with hydroxide ion in water revealed that the reactions are complex and involve kinetically significant intermediates. Kinetic experiments at the isosbestic points where changes in reactant and product absorbance cancel indicate the evolution and decay of absorbance characteristic of ...