Aim: To compare the antimicrobial efficacy of five Medicinal plant extracts against two strains of Streptococcus mutans causing dental caries using Agar well diffusion method. Materials and methods: Five plant extracts were prepared by soxhlet extraction method using organic solvent. These extracts were tested against Streptococcus mutans MTCC 497& MTCC 890 causing dental caries by Agar well di...

Zanthoxylum ailanthoides (ZA) has been used as folk medicines in East Asian and recently reported to have several bioactivity; however, the studies of ZA on the regulation of triacylglycerol (TG) biosynthesis have not been elucidated yet. In this study, we examined whether the methanol extract of ZA (ZA-M) could reduce oleic acid- (OA-) induced intracellular lipid accumulation and confirmed its...

A new species of Calogalesus Kieffer, 1912, Calogalesus sinicussp. n., is described and illustrated, collected from a Chinese prickly ash (Zanthoxylum bungeanum Maxim.) orchard in Yunnan province of China. This is the third described species of the genus in the World. The new species can be distinguished from the other two described Calogalesus species by the head profile, proportions of the an...

Background: The Zanthoxylum monogynum species belongs to the family Rutaceae and is found in Southeast, Midwest, and Northeast Brazil. For this genus several biological activities have been described. Methods: The essential oil (EO) was obtained from the leaves of Zanthoxylum monogynum by hydro-distillation and was analyzed by gas chromatograph and gas chromatograph/mass spectrometry (GC and GC...

BACKGROUND Medicinal plants offer cheaper and safer treatment options to current diabetic drugs. The present study evaluated the effect of aqueous root bark extract of Zanthoxylum chalybeum on oral glucose tolerance and pancreas histopathology in alloxanized rats. METHOD Diabetes was induced in rats by administration of alloxan monohydrate. Root extract of Z. chalybeum was administered to rat...

This study focused on a promising drug candidate, N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-acrylamide (gx-50), a compound extracted from Sichuan pepper (Zanthoxylum Bungeanum), to determine whether it would be an effective therapeutic for Alzheimer's disease (AD) via biological experiments. In vivo, we determined the pharmacokinetic profile of gx-50 and evaluated the effect of gx-50 on the cog...

Breast carcinoma is a heterogeneous complex disease thought to occur via a multistep process, which despite improvements in surgery and the use of adjuvant therapy, continues to be fatal in many patients. Metastatic disease is the most common cause of breast cancer death. The genus Zanthoxylum is used as mouth fresh, tooth care, spice and possesses several types of biological activities. Zantho...