Sjogren's syndrome (SS) is defined by autoantibodies to Ro and La. The current studies identified additional autoantibodies in SS to salivary gland protein 1 (SP-1), carbonic anhydrase 6 (CA6) and parotid secretory protein (PSP). These autoantibodies were present in two animal models for SS and occurred earlier in the course of the disease than antibodies to Ro or La. Patients with SS also prod...

Patients suffering from a hypersensitivity syndrome (HS) caused by Trichloroethylene (TCE) have been reported mainly in Asian countries. However, due to its reported extremely low incidence rate, it’s rarely to encounter two patients from the same factory. We hospitalized two male cases who suffered from TCE-induced HS. Both patients developed exfoliative dermatitis, fever and liver dysfunction...

Hypokalemic acidosis can complicate a primary Sjögren’s syndrome. The clinical feature is rarely revealed by manifestations due to hypokalemia. We report the case of a 46-year-old woman, admitted to explore a paresthesia and paresis of inferior limbs. The diagnosis of Sjögren’s syndrome was retained since there was the association of xerophthalmia, sialadenitis at the labial biopsy and positive...

PURPOSE To determine the effects of the proinflammatory cytokines interleukin (IL)-1alpha, IL-1beta, and tumor necrosis factor (TNF)-alpha on neurally mediated lacrimal gland protein secretion and to determine whether the amount of IL-1beta protein is upregulated in inflamed lacrimal glands of the MRL/lpr mouse, a murine model of human Sjögren syndrome. METHODS Lacrimal gland lobules of BALB/...

Introduction: Severe acute malnutrition (SAM) is one of the main public health problems in world. It responsible addition to general symptoms, vitamin A deficiency which can cause serious eye damage including keratomalacia. This work aims study possible ophthalmological lesions severely acutely malnourished children from 0 60 months. Patients and Method: was carried out a secondary ophthalmolog...

Purpose: To determine the effect of combined use sodium hyaluronate and recombinant human epidermal growth factor (rhEGF) on xerophthalmia in elderly patients after cataract surgery, as well levels serum inflammatory factors.
 Methods: A total 84 diagnosed with phacoemulsification were retrospectively studied. The comprised two groups: control group consisting 40 given basic therapy using ...

Background: The aim of the study was to evaluate incidence xerophthalmia in individuals with glaucoma by administering a topical regimen antiglaucoma medication containing timolol and dorzolamide determine frequency ocular surface abnormalities among who are undergoing treatment medications. Methods: included total 75 participants both genders. A 50 units from 25 subjects under two or more agen...