Choosing appropriate client architectures is a hotly debated topic of late. Having been party to these debates and also to implementations using all three approaches, it is evident that some of the perceptions surrounding this debate don’t conform to reality. During actual implementation, particularly since the Hybrid approach is a mix of the two other approaches, some benefits and drawbacks in...

background: diabetes has a high prevalence in iran and it is estimated to rise from 3.5 million adults in 2005 to 5.1 million by 2025. given the high prevalence of diabetes in iranians, it is surprising how little is known about understanding of diabetes in public population. this study aimed to explore and describe people without diabetes explanation for the disease. materials and methods: thi...

Stillbirths contribute substantially to perinatal mortality in developed countries.1 Their prevalence ranges between 4 and 6 per 1000 births.1–3 Despite careful investigation, at least 25%,4 and possibly 50%,1 remain unexplained. Another mysterious cause of early sudden death is represented by sudden infant death syndrome (SIDS),5,6 which is still the leading cause of mortality during the first...

2. Can you get to places beyond walking distance without help with some help Or are you completely unable to travel unless special arrangements are made? [ ] 3 [ ] 2 [ ] 1 3. Can you go shopping for groceries without help with some help Or are you completely unable to do any shopping? [ ] 3 [ ] 2 [ ] 1 4. Can you prepare your own meals without help with some help Or are you completely unable to...

Over time, IT infrastructures have become increasingly complex and costly to manage and operate. Oracle’s end-to-end, integrated, industry-leading infrastructure solutions for SAP let you simplify your IT environment so you can drive more business value. With a high-performance, robust, open, and flexible SAP infrastructure based on Oracle solutions, you can leverage the power of virtualization...

Scleroderma renal crisis has been documented as the presenting manifestation of systemic sclerosis sine scleroderma in pregnancy only once in the literature. Unfortunately, since scleroderma renal crisis in sine scleroderma pregnant patients is so rare, that patient expired. We present a case of a sine scleroderma pregnant patient with an initial manifestation of scleroderma renal crisis surviv...

This guidance describes how the FDA evaluates patient-reported outcome (PRO) instruments used as effectiveness endpoints in clinical trials. It also describes our current thinking on how sponsors can develop and use study results measured by PRO instruments to support claims in approved product labeling (see appendix point 1). It does not address the use of PRO instruments for purposes beyond e...

Clustering is very problematic on big data set in synchronous programming as well as time consuming. Finding optimal result from big misaligned data set is precarious because lack of seamless data pattern. This study emphasizes on reducing time fact and deployment of asynchronous program rather than synchronous model on big data. However, we provide an easy and flexible model named Unified Asyn...

Some ratio estimators for estimating the population mean of the variable under study, which make use of information regarding the population proportion possessing certain attribute, are proposed. Under simple random sampling without replacement (SRSWOR) scheme, the expressions of bias and mean-squared error (MSE) up to the first order of approximation are derived. The results obtained have been...