Sequence-specific binding to DNA is crucial for targeting transcription factor-DNA complexes to modulate gene expression. The heterocyclic diamidine, DB2277, specifically recognizes a single G•C base pair in the minor groove of mixed base pair sequences of the type AAAGTTT. NMR spectroscopy reveals the presence of major and minor species of the bound compound. To understand the principles that ...

In this note we investigate some matroid minor structure results. In particular, we present sufficient conditions, in terms of triangles, for a matroid to have either U2,4 or F7 or M(K5) as a minor.

The Collins-Soper kernel is a powerful tool for studying the properties of QCD vacuum and an essential component transverse momentum dependent (TMD) factorization theorem. In this paper, we present novel method determining directly from comparison differential cross sections measured at different energies. relies solely on structure TMD theorem thus also provides direct test validity. With mino...

background: tricyclic antidepressants (tcas) poisoning is the most common poisoning in the poisoning emergency department of noor hospital, isfahan, iran. the objective of this study was to compare qrs interval duration with ravr³3mm and r/savr³ 0.7 in predicting: serious complications of acute tca toxicity. methods and materials: this study was descriptive – analytic and prospective cohort. tc...

BACKGROUND Cytomegalovirus (CMV) pneumonitis has been shown to be associated with lymphocytic alveolitis after lung transplantation. In the present study, we investigated a series of bronchoalveolar (BAL) and blood samples, collected in the absence of rejection or acute infectious episodes. in order -1: to evaluate intra-alveolar cell population changes concomitant with CMV replication and -2: ...

Hope is an important variable in mental health, particularly in the emergent field of research focused on recovery and well-being. This study validates the "Integrative Hope Scale" (IHS) for use in people with severe mental illness. Two hundred participants diagnosed with schizophrenia or schizoaffective disorder were assessed using the IHS, the Centre for Epidemiological Studies Depression Sca...

Strontium-substituted Ca10(PO4)6(OH)2 hydroxyapatite (HAp) powders, with Sr wt% concentrations of 2.5, 5.6 and 10%, were prepared by a solid-state synthesis method. The chemical composition the samples was accurately evaluated using inductively coupled plasma (ICP) spectroscopy. morphology analyzed via optical microscopy, while structural characterization achieved through powder X-ray diffracti...

BACKGROUND Pediatric ADHD is associated with impairments in working memory, but these deficits often go undetected when using clinic-based tests such as digit span backward. AIMS The current study pilot-tested minor administration/scoring modifications to improve digit span backward's construct and predictive validities in a well-characterized sample of children with ADHD. METHODS AND PROCE...