in this syudy a continuous bovine kidney cell line derived from a primary bovine kidney cells was established for the first time in iran. the cells were originating from two-day-old normal male calf of holstein breed. the cell cultures were continuously passaged following complete proliferation of primary cells. the specific properties or characteristics of the cell were defined using cytogene...

Three years after the creation of the Pasteur Institute in Paris (1888), Albert Calmette, a French doctor in the Corps de Sante des Colonies, laid the foundations of its first overseas daughter institute in Cochin-China, a distant French colony. In fact, the Australian Pasteur Institute could also lay claim to be considered the first, as Pasteur's own nephew, Adrien Loir,' began plans for it as...

Until the first decade of this century, our information about epidemic, i.e., exanthematic typhus was rather scarce. We knew only that there existed a very dangerous, easily communicable disease, which decimated populations during wars, hunger, or flood, spreading with great speed and affecting large numbers of people. After World War I, 20-30 million people died in Eastern Europe from this dis...

1 Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran, Tehran, Iran, 2 Microbiology Research Center, Pasteur Institute of Iran, Tehran, Iran, 3 Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran, 4 Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran...

objective: the rifampicin resistance and susceptibility of mycobacterium tuberculosis are caused by mutations in the 81-base pair region of the rpob gene encoding the b-subunit of rna polymerase. methods: isoniazid resistance of m. tuberculosis is related to mutations in inha , oxyr and ahpc genes which 30 to 90 percent of isoniazid resistance is occurred in 3015 codons of katg gene. the rpob a...