BACKGROUND Tumor-related leukocytosis (TRL) is occasionally found in patients with nonhematopoietic malignancies. We investigated the clinical implication of TRL and individualized treatment for TRL-positive cervical cancer, as well as the underlying biological mechanism. METHODS Clinical data from 258 cervical cancer patients treated with definitive radiotherapy were analyzed to investigate ...

Ridit analysis has been used by a variety of investigators (e.g., 1-5) and has appeared in a t least one textbook (6). Bross (7) introduced the technique of ridit analysis and Kantor et a1 (8) showed the relationship between the average ridit value and a quantile rank. The purpose of this article is to elaborate on the remark made by Bross (7) that "[ridit analysis is] closely related to distri...

OBJECTIVE A method that would allow in situ comparison of the degrees of adherence to genital epithelia by the biofilms of the normal flora. SUBJECTS Four healthy women. SETTING Departments of Biological Sciences, University of Calgary, and of Medicine, University of British Columbia. METHODS In situ, scraped specimens were taken from the vagina and ectocervix before and after vigorous va...

This procedure allows you to study the power and sample size of tests of equivalence of means of two correlated variables. Schuirmann’s (1987) two one-sided tests (TOST) approach is used to test equivalence. The paired t-test is commonly used in this situation. Other tests have been developed for the case when the data are not normally distributed. These additional tests include the Wilcoxon si...

Baseline differences between patients without heart disease (HD) and with HD were assessed by the chi-squared test for categorical data. Quantitative data were tested for normality using the Kolmogorov–Smirnov test. The t-test was used to test differences for normally distributed data; otherwise the Wilcoxon rank-sum test was used. Clinical baseline data comparing these groups are visualized in...

BACKGROUND Thyroid adenoma associated (THADA) has been identified as the target gene affected by chromosome 2p21 translocations in thyroid adenomas, but the role of THADA in the thyroid is still elusive. The aim of this study was to quantify THADA gene expression in normal tissues and in thyroid hyper- and neoplasias, using real-time PCR. METHODS For the analysis THADA and 18S rRNA gene expre...

The assessment of overall homogeneity of time-to-event curves is a key element in survival analysis in biomedical research. The currently commonly used testing methods, e.g. log-rank test, Wilcoxon test, and Kolmogorov-Smirnov test, may have a significant loss of statistical testing power under certain circumstances. In this paper we propose a new testing method that is robust for the compariso...

The efficiency of an alternative method of collection (by suction of water) for the study of Culicidae and Chironomidae (Diptera), Scirtidae (Coleoptera) and Coenagrionidae (Odonata) in bromeliads with different foliar architecture in a restinga at Florianópolis, SC, Brazil, was studied. The alternative method was less efficient to collect Culicidae and Chironomidae (Wilcoxon test p < 0.05) and...

Methods Ten patients with adult-onset GHD and ageand sexmatched controls (n=10) underwent CMR. Patients underwent scans before disease treatment and at twelve months after treatment. Cardiac parameters were calculated and indexed to body surface area (BSA). The comparison between groups was done using Mann-UWhitney test and within the group using Wilcoxon test. The data are presented as median ...

The exact critical points for selected sample sizes and significance levels are tabulated for the two-sample test statistic which is a combination of the Wilcoxon and the Mood test statistic. This statistic serves for testing the null hypothesis that two sampled populations have the same location and scale parameters.